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Micromachines 2015, 6(1), 136-150; doi:10.3390/mi6010136

Optimized Simulation and Validation of Particle Advection in Asymmetric Staggered Herringbone Type Micromixers

1
Faculty of Information Technology and Bionics, Pázmány Péter Catholic University, Práter utca 50/a, H-1083 Budapest, Hungary
2
Research Centre for Natural Sciences, Institute for Technical Physics and Materials Science, Hungarian Academy of Sciences, Konkoly Thege M. út 29-33, H-1121 Budapest, Hungary
*
Author to whom correspondence should be addressed.
Academic Editor: Yong Kweon Suh
Received: 23 October 2014 / Accepted: 16 December 2014 / Published: 30 December 2014
(This article belongs to the Special Issue Micromixer & Micromixing)
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Abstract

This paper presents and compares two different strategies in the numerical simulation of passive microfluidic mixers based on chaotic advection. In addition to flow velocity field calculations, concentration distributions of molecules and trajectories of microscale particles were determined and compared to evaluate the performance of the applied modeling approaches in the proposed geometries. A staggered herringbone type micromixer (SHM) was selected and studied in order to demonstrate finite element modeling issues. The selected microstructures were fabricated by a soft lithography technique, utilizing multilayer SU-8 epoxy-based photoresist as a molding replica for polydimethylsiloxane (PDMS) casting. The mixing processes in the microfluidic systems were characterized by applying molecular and particle (cell) solutions and adequate microscopic visualization techniques. We proved that modeling of the molecular concentration field is more costly, in regards to computational time, than the particle trajectory based method. However, both approaches showed adequate qualitative agreement with the experimental results. View Full-Text
Keywords: staggered herringbone micromixer (SHM); concentration distribution; particle trajectory; finite element modeling; experimental validation staggered herringbone micromixer (SHM); concentration distribution; particle trajectory; finite element modeling; experimental validation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Tóth, E.L.; Holczer, E.G.; Iván, K.; Fürjes, P. Optimized Simulation and Validation of Particle Advection in Asymmetric Staggered Herringbone Type Micromixers. Micromachines 2015, 6, 136-150.

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