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Micromachines 2013, 4(1), 103-115; doi:10.3390/mi4010103

Microbeads for Sampling and Mixing in a Complex Sample

1
Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332, USA
2
School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA
3
Center for Food Safety, Department of Food Science & Technology, University of Georgia, Griffin, GA 30223, USA
*
Author to whom correspondence should be addressed.
Received: 21 January 2013 / Revised: 4 March 2013 / Accepted: 5 March 2013 / Published: 19 March 2013
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Abstract

This paper presents work on the development of a microfluidic device using super-paramagnetic beads for sampling and mixing. The beads are manipulated via an external rotating permanent magnet in a microfluidic channel. Efficient mixing is achieved in a short distance with this method. Modeling shows the variables which influence the mixing are flow rate, bead rotation speed and the bead number density. Displacement of the bead relative the rotating magnetic field sets an upper limit on the bead rotation speed due to viscous drag. Future work will examine optimization of this system for capture of pathogens from a complex mixture.
Keywords: microfluidics; convective mixing; magnetic microbeads; complex sample microfluidics; convective mixing; magnetic microbeads; complex sample
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Owen, D.; Mao, W.; Alexeev, A.; Cannon, J.L.; Hesketh, P.J. Microbeads for Sampling and Mixing in a Complex Sample. Micromachines 2013, 4, 103-115.

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