- freely available
Yessotoxin as a Tool to Study Induction of Multiple Cell Death Pathways
AbstractThis work proposes to use the marine algal toxin yessotoxin (YTX) to establish reference model experiments to explore medically valuable effects from induction of multiple cell death pathways. YTX is one of few toxins reported to make such induction. It is a small molecule compound which at low concentrations can induce apoptosis in primary cultures, many types of cells and cell lines. It can also induce a non-apoptotic form of programmed cell death in BC3H1 myoblast cell lines. The present contribution reviews arguments that this type of induction may have principal interest outside this particular example. One principal effect of medical interest may be that cancer cells will not so easily adapt to the synergistic effects from induction of more than one death pathway as compared to induction of only apoptosis.
Share & Cite This Article
Export to BibTeX | EndNote
MDPI and ACS Style
Korsnes, M.S. Yessotoxin as a Tool to Study Induction of Multiple Cell Death Pathways. Toxins 2012, 4, 568-579.View more citation formats
Korsnes MS. Yessotoxin as a Tool to Study Induction of Multiple Cell Death Pathways. Toxins. 2012; 4(7):568-579.Chicago/Turabian Style
Korsnes, Mónica Suárez. 2012. "Yessotoxin as a Tool to Study Induction of Multiple Cell Death Pathways." Toxins 4, no. 7: 568-579.