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Toxins 2010, 2(7), 1690-1703; doi:10.3390/toxins2071690
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Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins

1,*  and 2
Received: 4 May 2010 / Revised: 14 June 2010 / Accepted: 28 June 2010 / Published: 29 June 2010
(This article belongs to the Special Issue Enterotoxins)
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Abstract

Bacillus cereus behaves as an opportunistic pathogen frequently causing gastrointestinal diseases, and it is increasingly recognized to be responsible for severe local or systemic infections. Pathogenicity of B. cereus mainly relies on the secretion of a wide array of toxins and enzymes and also on the ability to undergo swarming differentiation in response to surface-sensing. In this report, the pathogenicity exerted by B. cereus toxins is described with particular attention to the regulatory mechanisms of production and secretion of HBL, Nhe and CytK enterotoxins.
Keywords: hemolysin BL; non-hemolytic enterotoxin; cytotoxin K; B. cereus hemolysin BL; non-hemolytic enterotoxin; cytotoxin K; B. cereus
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Senesi, S.; Ghelardi, E. Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins. Toxins 2010, 2, 1690-1703.

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