Toxins 2010, 2(7), 1690-1703; doi:10.3390/toxins2071690
Review

Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins

Sonia Senesi 1,* email and Emilia Ghelardi 2 email
1 Dipartimento di Biologia,University of Pisa, via S. Zeno 37, 56127 Pisa, Italy 2 Dipartimento di Patologia Sperimentale, Biotecnologie Mediche, Infettivologia ed Epidemiologia, University of Pisa, via S. Zeno 37, 56127 Pisa, Italy
* Author to whom correspondence should be addressed.
Received: 4 May 2010; in revised form: 14 June 2010 / Accepted: 28 June 2010 / Published: 29 June 2010
(This article belongs to the Special Issue Enterotoxins)
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Abstract: Bacillus cereus behaves as an opportunistic pathogen frequently causing gastrointestinal diseases, and it is increasingly recognized to be responsible for severe local or systemic infections. Pathogenicity of B. cereus mainly relies on the secretion of a wide array of toxins and enzymes and also on the ability to undergo swarming differentiation in response to surface-sensing. In this report, the pathogenicity exerted by B. cereus toxins is described with particular attention to the regulatory mechanisms of production and secretion of HBL, Nhe and CytK enterotoxins.
Keywords: hemolysin BL; non-hemolytic enterotoxin; cytotoxin K; B. cereus

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Cite This Article

MDPI and ACS Style

Senesi, S.; Ghelardi, E. Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins. Toxins 2010, 2, 1690-1703.

AMA Style

Senesi S, Ghelardi E. Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins. Toxins. 2010; 2(7):1690-1703.

Chicago/Turabian Style

Senesi, Sonia; Ghelardi, Emilia. 2010. "Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins." Toxins 2, no. 7: 1690-1703.

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