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Ascorbic Acid and the Brain: Rationale for the Use against Cognitive Decline
AbstractThis review is focused upon the role of ascorbic acid (AA, vitamin C) in the promotion of healthy brain aging. Particular attention is attributed to the biochemistry and neuronal metabolism interface, transport across tissues, animal models that are useful for this area of research, and the human studies that implicate AA in the continuum between normal cognitive aging and age-related cognitive decline up to Alzheimer’s disease. Vascular risk factors and comorbidity relationships with cognitive decline and AA are discussed to facilitate strategies for advancing AA research in the area of brain health and neurodegeneration.
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Harrison, F.E.; Bowman, G.L.; Polidori, M.C. Ascorbic Acid and the Brain: Rationale for the Use against Cognitive Decline. Nutrients 2014, 6, 1752-1781.View more citation formats
Harrison FE, Bowman GL, Polidori MC. Ascorbic Acid and the Brain: Rationale for the Use against Cognitive Decline. Nutrients. 2014; 6(4):1752-1781.Chicago/Turabian Style
Harrison, Fiona E.; Bowman, Gene L.; Polidori, Maria C. 2014. "Ascorbic Acid and the Brain: Rationale for the Use against Cognitive Decline." Nutrients 6, no. 4: 1752-1781.