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Macular Pigment and Its Contribution to Vision
Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
Institute of Vision Research, Whitfield Clinic, Waterford, Ireland
Howard Foundation, Downing College, Cambridge University, Cambridge, CB22 5LA, UK
* Author to whom correspondence should be addressed.
Received: 26 March 2013; in revised form: 26 April 2013 / Accepted: 15 May 2013 / Published: 29 May 2013
Abstract: Three dietary carotenoids, lutein (L), zeaxanthin (Z) and meso-zeaxanthin (MZ) accumulate at the central retina (macula), where they are collectively referred to as macular pigment (MP). MP’s pre-receptoral absorption of blue light and consequential attenuation of the effects of chromatic aberration and light scatter are important for optimal visual function. Furthermore, antioxidant activity of MP’s constituent carotenoids and the same blue light-filtering properties underlie the rationale for its putative protective role for age-related macular degeneration (AMD). Supplementation with L, Z and MZ augments MP and enhances visual performance in diseased and non-diseased eyes, and may reduce risk of AMD development and/or progression.
Keywords: lutein; zeaxanthin; meso-zeaxanthin; visual performance; macular pigment
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Cite This Article
MDPI and ACS Style
Loskutova, E.; Nolan, J.; Howard, A.; Beatty, S. Macular Pigment and Its Contribution to Vision. Nutrients 2013, 5, 1962-1969.
Loskutova E, Nolan J, Howard A, Beatty S. Macular Pigment and Its Contribution to Vision. Nutrients. 2013; 5(6):1962-1969.
Loskutova, Ekaterina; Nolan, John; Howard, Alan; Beatty, Stephen. 2013. "Macular Pigment and Its Contribution to Vision." Nutrients 5, no. 6: 1962-1969.