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Nutritional Management of Insulin Resistance in Nonalcoholic Fatty Liver Disease (NAFLD)
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
Division of Gastroenterology and Clinical Nutrition; Department of Internal Medicine, Montefiore Medical Center (Wakefield), 2425 Eastchester Road, Bronx, NY, 10469, USA
* Author to whom correspondence should be addressed.
Received: 18 May 2013; in revised form: 14 August 2013 / Accepted: 19 September 2013 / Published: 11 October 2013
Abstract: Nonalcoholic fatty liver disease (NAFLD) is an emerging global health concern. It is the most common form of chronic liver disease in Western countries, affecting both adults and children. NAFLD encompasses a broad spectrum of fatty liver disease, ranging from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH), and is strongly associated with obesity, insulin resistance, and dyslipidemia. First-line therapy for NAFLD includes weight loss achieved through diet and physical activity. However, there is a lack of evidenced-based dietary recommendations. The American Diabetes Association’s (ADA) recommendations that aim to reduce the risk of diabetes and cardiovascular disease may also be applicable to the NAFLD population. The objectives of this review are to: (1) provide an overview of NAFLD in the context of insulin resistance, and (2) provide a rationale for applying relevant aspects of the ADA recommendations to the nutritional management of NAFLD.
Keywords: nonalcoholic fatty liver disease; nonalcoholic steatohepatitis; hepatic steatosis; insulin resistance; diabetes; nutrition; macronutrients; review
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MDPI and ACS Style
Conlon, B.A.; Beasley, J.M.; Aebersold, K.; Jhangiani, S.S.; Wylie-Rosett, J. Nutritional Management of Insulin Resistance in Nonalcoholic Fatty Liver Disease (NAFLD). Nutrients 2013, 5, 4093-4114.
Conlon BA, Beasley JM, Aebersold K, Jhangiani SS, Wylie-Rosett J. Nutritional Management of Insulin Resistance in Nonalcoholic Fatty Liver Disease (NAFLD). Nutrients. 2013; 5(10):4093-4114.
Conlon, Beth A.; Beasley, Jeannette M.; Aebersold, Karin; Jhangiani, Sunil S.; Wylie-Rosett, Judith. 2013. "Nutritional Management of Insulin Resistance in Nonalcoholic Fatty Liver Disease (NAFLD)." Nutrients 5, no. 10: 4093-4114.