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• Nazzaro, F
• Orlando, P
• Fratianni, F
• Di Luccia, A
• Coppola, R
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• Nazzaro, F
• Orlando, P
• Fratianni, F
• Di Luccia, A
• Coppola, R
• [+] on PubMed
• Nazzaro, F
• Orlando, P
• Fratianni, F
• Di Luccia, A
• Coppola, R

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Nutrients 2012, 4(10), 1475-1489; doi:10.3390/nu4101475

Review

Protein Analysis-on-Chip Systems in Foodomics

Filomena Nazzaro ^1,* , Pierangelo Orlando ² , Florinda Fratianni ¹ , Aldo Di Luccia ^1,3  and Raffaele Coppola ¹

¹ Institute of Food Science, ISA-CNR, Via Roma 64, Avellino 83100, Italy ² Institute of Protein Biochemistry, IBP-CNR, Via P. Castellino 121, Napoli 80124, Italy ³ Department of Food Science, University of Foggia, Via Napoli 25, Foggia 71100, Italy

* Author to whom correspondence should be addressed.

Received: 22 May 2012; in revised form: 21 July 2012 / Accepted: 30 September 2012 / Published: 16 October 2012

(This article belongs to the Special Issue Foodomics 2011)

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Abstract: Protein compositional data can address nutritional, packaging, origin/authenticity, processing history, safety and other quality questions. Such data has been time-consuming and expensive to generate until recently but “protein analysis on a chip” systems are now available that can analyze a complex food sample in a few minutes and do not require great protein analytical expertise. We review some of the main new approaches with examples of their application and discuss their advantages and disadvantages.

Keywords: lab-on-chip; protein; microisoelectrofocusing; proteomic; food

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