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Viruses 2017, 9(5), 102; doi:10.3390/v9050102

The Broad Host Range and Genetic Diversity of Mammalian and Avian Astroviruses

1
Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia
2
Duke-NUS Medical School, Singapore 169857, Singapore
*
Author to whom correspondence should be addressed.
Academic Editor: Stacey Schultz-Cherry
Received: 31 March 2017 / Revised: 5 May 2017 / Accepted: 7 May 2017 / Published: 10 May 2017
(This article belongs to the Special Issue Astroviruses)
View Full-Text   |   Download PDF [1234 KB, uploaded 10 May 2017]   |  

Abstract

Astroviruses are a diverse family of viruses that infect a wide range of mammalian and avian hosts. Here we describe the phylogenetic diversity and current classification methodology of astroviruses based on the ORF1b and ORF2 genes, highlighting the propensity of astroviruses to undergo interspecies transmission and genetic recombination which greatly increase diversity and complicate attempts at a unified and comprehensive classification strategy. View Full-Text
Keywords: astrovirus; classification; avian; mammal; genetic diversity; capsid; RNA-dependent-RNA-polymerase; ORF1b; ORF2 astrovirus; classification; avian; mammal; genetic diversity; capsid; RNA-dependent-RNA-polymerase; ORF1b; ORF2
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Donato, C.; Vijaykrishna, D. The Broad Host Range and Genetic Diversity of Mammalian and Avian Astroviruses. Viruses 2017, 9, 102.

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