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Viruses 2010, 2(6), 1279-1305; doi:10.3390/v2061279
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Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections

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Received: 9 March 2010 / Revised: 18 May 2010 / Accepted: 25 May 2010 / Published: 31 May 2010
(This article belongs to the Special Issue Hepatitis Viruses)
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Abstract

While 25 compounds have been formally licensed for the treatment of HIV infection (AIDS), only seven licensed products are currently available for the treatment of chronic hepatitis B virus (HBV) infection: interferon-α, pegylated interferon-α, lamivudine, adefovir (dipivoxil), entecavir, telbivudine and tenofovir (disoproxil fumarate). In contrast to the treatment of HIV infections where the individual drugs are routinely used in combination, for the treatment of chronic HBV infection the individual drugs are generally used in monotherapy. In principle, combination drug therapy should allow reducing the likelihood of drug-resistant development.
Keywords: antiviral therapy; HBV therapy; nucleoside analogs; viral hepatitis antiviral therapy; HBV therapy; nucleoside analogs; viral hepatitis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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De Clercq, E.; Férir, G.; Kaptein, S.; Neyts, J. Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections. Viruses 2010, 2, 1279-1305.

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