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Materials 2016, 9(4), 288; doi:10.3390/ma9040288

Bioactive Glass Nanoparticles: From Synthesis to Materials Design for Biomedical Applications

1
SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, Université Clermont Auvergne, BP 10448, Clermont-Ferrand F-63000, France
2
CNRS, UMR 6296, ICCF, Aubiere F-63178, France
*
Author to whom correspondence should be addressed.
Academic Editor: Gigliola Lusvardi
Received: 9 March 2016 / Revised: 8 April 2016 / Accepted: 11 April 2016 / Published: 14 April 2016
(This article belongs to the Special Issue Bioactive Glasses)
View Full-Text   |   Download PDF [1760 KB, uploaded 14 April 2016]   |  

Abstract

Thanks to their high biocompatibility and bioactivity, bioactive glasses are very promising materials for soft and hard tissue repair and engineering. Because bioactivity and specific surface area intrinsically linked, the last decade has seen a focus on the development of highly porous and/or nano-sized materials. This review emphasizes the synthesis of bioactive glass nanoparticles and materials design strategies. The first part comprehensively covers mainly soft chemistry processes, which aim to obtain dispersible and monodispersed nanoparticles. The second part discusses the use of bioactive glass nanoparticles for medical applications, highlighting the design of materials. Mesoporous nanoparticles for drug delivery, injectable systems and scaffolds consisting of bioactive glass nanoparticles dispersed in a polymer, implant coatings and particle dispersions will be presented. View Full-Text
Keywords: bioactive glass; nanoparticles; sol-gel; biomedical applications bioactive glass; nanoparticles; sol-gel; biomedical applications
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Vichery, C.; Nedelec, J.-M. Bioactive Glass Nanoparticles: From Synthesis to Materials Design for Biomedical Applications. Materials 2016, 9, 288.

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