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Materials 2016, 9(4), 287; doi:10.3390/ma9040287

A Novel MgO-CaO-SiO2 System for Fabricating Bone Scaffolds with Improved Overall Performance

1
State Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China
2
School of Basic Medical Science, Central South University, Changsha 410078, China
3
College of Chemistry, Xiangtan University, Xiangtan 411105, China
4
Department of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha 410011, China
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Juergen Stampfl
Received: 18 March 2016 / Revised: 5 April 2016 / Accepted: 8 April 2016 / Published: 14 April 2016
(This article belongs to the Section Biomaterials)
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Abstract

Although forsterite (Mg2SiO4) possesses good biocompatibility and suitable mechanical properties, the insufficient bioactivity and degradability hinders its further application. In this study, a novel MgO-CaO-SiO2 system was developed by adding wollastonite (CaSiO3) into Mg2SiO4 to fabricate bone scaffolds via selective laser sintering (SLS). The apatite-forming ability and degradability of the scaffolds were enhanced because the degradation of CaSiO3 could form silanol groups, which could offer nucleation sites for apatite. Meanwhile, the mechanical properties of the scaffolds grew with increasing CaSiO3 to 20 wt %. It was explained that the liquid phase of CaSiO3 promoted the densification during sintering due to its low melting point. With the further increase in CaSiO3, the mechanical properties decreased due to the formation of the continuous filling phase. Furthermore, the scaffolds possessed a well-interconnected porous structure and exhibited an ability to support cell adhesion and proliferation. View Full-Text
Keywords: MgO-CaO-SiO2 system; forsterite; wollastonite; scaffold; overall performance MgO-CaO-SiO2 system; forsterite; wollastonite; scaffold; overall performance
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Sun, H.; He, S.; Wu, P.; Gao, C.; Feng, P.; Xiao, T.; Deng, Y.; Shuai, C. A Novel MgO-CaO-SiO2 System for Fabricating Bone Scaffolds with Improved Overall Performance. Materials 2016, 9, 287.

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