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Materials 2013, 6(12), 5675-5689; doi:10.3390/ma6125675

Comparative Osteogenesis of Radiopaque Dicalcium Silicate Cement and White-Colored Mineral Trioxide Aggregate in a Rabbit Femur Model

1
School of Dentistry, Chung Shan Medical University, Taichung City 402, Taiwan
2
Department of Dentistry, Chung Shan Medical University Hospital, Taichung City 402, Taiwan
3
Institute of Oral Science, Chung Shan Medical University, Taichung City 402, Taiwan
*
Author to whom correspondence should be addressed.
Received: 29 August 2013 / Revised: 21 October 2013 / Accepted: 2 December 2013 / Published: 5 December 2013
(This article belongs to the Special Issue Ceramics for Healthcare 2013)
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Abstract

The radiopaque dicalcium silicate cement (RDSC) displayed a shortened setting time and good biocompatibility. This study aimed to compare the regenerative potential of RDSC and white-colored mineral trioxide aggregate (WMTA) using a rabbit femur model. The animals were sacrificed at one, three and six months to accomplish histological and biochemical analyses. The results indicated that after one month of implantation, WMTA was associated with a greyish color alteration within its mass, while RDSC presented color stability even at six months. Histological assay with Masson’s Trichrome and Von Kossa stains showed the presence of newly formed bone surrounding the implanted sites in the rabbit femur. The histochemical data revealed that the RDSC group had significantly more bone regeneration than did the WMTA groups at three and six months. The conclusion drawn is that the encouraging results support the potential applications of RDSC as an improved alternative to WMTA for endodontic uses. View Full-Text
Keywords: calcium silicate cement; root-end filling material; mineral trioxide aggregate; in vivo calcium silicate cement; root-end filling material; mineral trioxide aggregate; in vivo
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Wu, B.-C.; Huang, S.-C.; Ding, S.-J. Comparative Osteogenesis of Radiopaque Dicalcium Silicate Cement and White-Colored Mineral Trioxide Aggregate in a Rabbit Femur Model. Materials 2013, 6, 5675-5689.

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