Materials 2013, 6(12), 5675-5689; doi:10.3390/ma6125675
Article

Comparative Osteogenesis of Radiopaque Dicalcium Silicate Cement and White-Colored Mineral Trioxide Aggregate in a Rabbit Femur Model

1email, 1email and 2,3,* email
Received: 29 August 2013; in revised form: 21 October 2013 / Accepted: 2 December 2013 / Published: 5 December 2013
(This article belongs to the Special Issue Ceramics for Healthcare 2013)
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Abstract: The radiopaque dicalcium silicate cement (RDSC) displayed a shortened setting time and good biocompatibility. This study aimed to compare the regenerative potential of RDSC and white-colored mineral trioxide aggregate (WMTA) using a rabbit femur model. The animals were sacrificed at one, three and six months to accomplish histological and biochemical analyses. The results indicated that after one month of implantation, WMTA was associated with a greyish color alteration within its mass, while RDSC presented color stability even at six months. Histological assay with Masson’s Trichrome and Von Kossa stains showed the presence of newly formed bone surrounding the implanted sites in the rabbit femur. The histochemical data revealed that the RDSC group had significantly more bone regeneration than did the WMTA groups at three and six months. The conclusion drawn is that the encouraging results support the potential applications of RDSC as an improved alternative to WMTA for endodontic uses.
Keywords: calcium silicate cement; root-end filling material; mineral trioxide aggregate; in vivo
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Wu, B.-C.; Huang, S.-C.; Ding, S.-J. Comparative Osteogenesis of Radiopaque Dicalcium Silicate Cement and White-Colored Mineral Trioxide Aggregate in a Rabbit Femur Model. Materials 2013, 6, 5675-5689.

AMA Style

Wu B-C, Huang S-C, Ding S-J. Comparative Osteogenesis of Radiopaque Dicalcium Silicate Cement and White-Colored Mineral Trioxide Aggregate in a Rabbit Femur Model. Materials. 2013; 6(12):5675-5689.

Chicago/Turabian Style

Wu, Buor-Chang; Huang, Shu-Ching; Ding, Shinn-Jyh. 2013. "Comparative Osteogenesis of Radiopaque Dicalcium Silicate Cement and White-Colored Mineral Trioxide Aggregate in a Rabbit Femur Model." Materials 6, no. 12: 5675-5689.


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