Next Article in Journal
Environmentally Reformed Travel Habits During the 2006 Congestion Charge Trial in Stockholm—A Qualitative Study
Next Article in Special Issue
Street Connectivity is Negatively Associated with Physical Activity in Canadian Youth
Previous Article in Journal
Correction: Jia, C. and Batterman, S. A Critical Review of Naphthalene Sources and Exposures Relevant to Indoor and Outdoor Air. Int. J. Environ. Res. Public Health 2010, 7, 2903-2939
Previous Article in Special Issue
Aging Risk and Health Care Expenditure in Korea
Article Menu

Export Article

Open AccessArticle
Int. J. Environ. Res. Public Health 2011, 8(8), 3192-3201; doi:10.3390/ijerph8083192

Prevalence of Symptoms of Severe Asthma and Allergies in Irish School Children: An ISAAC Protocol Study, 1995–2007

Tobacco Free Research Institute, The Digital Depot, Thomas Street, Dublin 8, Ireland
Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin 2, Ireland
Asthma Society of Ireland, 42-43 Amiens Street, Dublin 1, Ireland
Dublin Institute of Technology, 143-149 Rathmines Road, Dublin 6, Ireland
Author to whom correspondence should be addressed.
Received: 5 May 2011 / Revised: 25 June 2011 / Accepted: 22 July 2011 / Published: 2 August 2011
(This article belongs to the Special Issue Health Behavior and Public Health)
View Full-Text   |   Download PDF [256 KB, uploaded 19 June 2014]


Childhood asthma is a recurring health burden and symptoms of severe asthma in children are also emerging as a health and economic issue. This study examined changing patterns in symptoms of severe asthma and allergies (ever eczema and hay fever), using the Irish International Study of Asthma and Allergies in Childhood (ISAAC) protocol. ISAAC is a cross-sectional self-administered questionnaire survey of randomly selected representative post-primary schools. Children aged 13–14 years were studied: 2,670 (in 1995), 2,273 (in 1998), 2,892 (in 2002–2003), and 2,805 (in 2007). Generalized linear modelling using Poisson distribution was employed to compute adjusted prevalence ratios (PR). A 39% significant increase in symptoms of severe asthma was estimated in 2007 relative to the baseline year 1995 (adjusted PR: 1.39 [95% CI: 1.14–1.69]) increasing from 12% in 1995 to 15.3% in 2007. Opposite trends were observed for allergies, showing a decline in 2007, with an initial rise. The potential explanations for such a complex disease pattern whose aetiological hypothesis is still evolving are speculative. Changing environmental factors may be a factor, for instance, an improvement in both outdoor and indoor air quality further reinforcing the hygiene hypothesis but obesity as a disease modifier must also be considered. View Full-Text
Keywords: allergies; asthma; Ireland; ISAAC; symptoms; severe asthma allergies; asthma; Ireland; ISAAC; symptoms; severe asthma
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Kabir, Z.; Manning, P.J.; Holohan, J.; Goodman, P.G.; Clancy, L. Prevalence of Symptoms of Severe Asthma and Allergies in Irish School Children: An ISAAC Protocol Study, 1995–2007. Int. J. Environ. Res. Public Health 2011, 8, 3192-3201.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top