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Int. J. Environ. Res. Public Health 2010, 7(5), 1913-1936; doi:10.3390/ijerph7051913
Review

Season of Birth and Risk for Adult Onset Glioma

Center for Health of Vulnerable Populations, Office of the Dean, School of Nursing, University of North Carolina, 237A McIver Building, Administrative Drive, Greensboro, NC 27402-6170, USA
Received: 6 January 2010 / Revised: 4 February 2010 / Accepted: 11 February 2010 / Published: 28 April 2010
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Abstract

Adult onset glioma is a rare cancer which occurs more frequently in Caucasians than African Americans, and in men than women. The etiology of this disease is largely unknown. Exposure to ionizing radiation is the only well established environmental risk factor, and this factor explains only a small percentage of cases. Several recent studies have reported an association between season of birth and glioma risk. This paper reviews the plausibility of evidence focusing on the seasonal interrelation of farming, allergies, viruses, vitamin D, diet, birth weight, and handedness. To date, a convincing explanation for the occurrence of adult gliomas decades after a seasonal exposure at birth remains elusive.
Keywords: gliomas; farming; allergies; handedness gliomas; farming; allergies; handedness
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Efird, J.T. Season of Birth and Risk for Adult Onset Glioma. Int. J. Environ. Res. Public Health 2010, 7, 1913-1936.

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Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert