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Season of Birth and Risk for Adult Onset Glioma
Center for Health of Vulnerable Populations, Office of the Dean, School of Nursing, University of North Carolina, 237A McIver Building, Administrative Drive, Greensboro, NC 27402-6170, USA
Received: 6 January 2010; in revised form: 4 February 2010 / Accepted: 11 February 2010 / Published: 28 April 2010
Abstract: Adult onset glioma is a rare cancer which occurs more frequently in Caucasians than African Americans, and in men than women. The etiology of this disease is largely unknown. Exposure to ionizing radiation is the only well established environmental risk factor, and this factor explains only a small percentage of cases. Several recent studies have reported an association between season of birth and glioma risk. This paper reviews the plausibility of evidence focusing on the seasonal interrelation of farming, allergies, viruses, vitamin D, diet, birth weight, and handedness. To date, a convincing explanation for the occurrence of adult gliomas decades after a seasonal exposure at birth remains elusive.
Keywords: gliomas; farming; allergies; handedness
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Efird, J.T. Season of Birth and Risk for Adult Onset Glioma. Int. J. Environ. Res. Public Health 2010, 7, 1913-1936.
Efird JT. Season of Birth and Risk for Adult Onset Glioma. International Journal of Environmental Research and Public Health. 2010; 7(5):1913-1936.
Efird, Jimmy T. 2010. "Season of Birth and Risk for Adult Onset Glioma." Int. J. Environ. Res. Public Health 7, no. 5: 1913-1936.