Int. J. Environ. Res. Public Health 2010, 7(3), 814-826; doi:10.3390/ijerph7030814

Molecular Epidemiology for Vector Research on Leishmaniasis

1,* email, 2email, 3,4email, 5email, 6email and 7email
Received: 9 December 2009; in revised form: 3 February 2010 / Accepted: 16 February 2010 / Published: 5 March 2010
(This article belongs to the Special Issue Advances in Epidemiology)
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Abstract: Leishmaniasis is a protozoan disease caused by the genus Leishmania transmitted by female phlebotomine sand flies. Surveillance of the prevalence of Leishmania and responsive vector species in endemic and surrounding areas is important for predicting the risk and expansion of the disease. Molecular biological methods are now widely applied to epidemiological studies of infectious diseases including leishmaniasis. These techniques are used to detect natural infections of sand fly vectors with Leishmania protozoa and are becoming powerful tools due to their sensitivity and specificity. Recently, genetic analyses have been performed on sand fly species and genotyping using PCR-RFLP has been applied to the sand fly taxonomy. In addition, a molecular mass screening method has been established that enables both sand fly species and natural leishmanial infections to be identified simultaneously in hundreds of sand flies with limited effort. This paper reviews recent advances in the study of sand flies, vectors of leishmaniasis, using molecular biological approaches.
Keywords: Leishmania; sand fly; epidemiology; mass screening
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MDPI and ACS Style

Kato, H.; Gomez, E.A.; Cáceres, A.G.; Uezato, H.; Mimori, T.; Hashiguchi, Y. Molecular Epidemiology for Vector Research on Leishmaniasis. Int. J. Environ. Res. Public Health 2010, 7, 814-826.

AMA Style

Kato H, Gomez EA, Cáceres AG, Uezato H, Mimori T, Hashiguchi Y. Molecular Epidemiology for Vector Research on Leishmaniasis. International Journal of Environmental Research and Public Health. 2010; 7(3):814-826.

Chicago/Turabian Style

Kato, Hirotomo; Gomez, Eduardo A.; Cáceres, Abraham G.; Uezato, Hiroshi; Mimori, Tatsuyuki; Hashiguchi, Yoshihisa. 2010. "Molecular Epidemiology for Vector Research on Leishmaniasis." Int. J. Environ. Res. Public Health 7, no. 3: 814-826.

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