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Int. J. Environ. Res. Public Health 2009, 6(4), 1530-1538; doi:10.3390/ijerph6041530
Article

Real World Study to Evaluate the Effectiveness of Varenicline and Cognitive-Behavioural Interventions for Smoking Cessation

1,*  and 2
Received: 10 March 2009; Accepted: 16 April 2009 / Published: 21 April 2009
(This article belongs to the Special Issue Tobacco Smoking and Public Health)
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Abstract: A prospective pragmatic interventional study was conducted to evaluate the effectiveness of varenicline for smoking cessation among a cohort of motivated smokers attending two smoking cessation clinics. Smokers between 18 and 65 years who had smoked 10 or more cigarettes per day were included. All participants received cognitive-behavioural varenicline according to approved dose and prescriptions. Continuous abstinence, validated by exhaled CO levels, was assessed in each control. A total of 264 smokers – 155 males (58.7%) and 109 females (41.3%) – were included. Mean age was 43.7, amount smoked was 23 cigarettes per day and 61.4% had at least one prior attempt to quit. The continuous abstinence rate at end of treatment (12 wks) was 58.3%. Conclusions: varenicline and cognitive-behavioural intervention are effective for smoking cessation with high continuous abstinence rates when are used in a clinical setting.
Keywords: Smoking cessation; varenicline; cognitive-behavioural intervention; continuous abstinence Smoking cessation; varenicline; cognitive-behavioural intervention; continuous abstinence
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Ramon, J.M.; Bruguera, E. Real World Study to Evaluate the Effectiveness of Varenicline and Cognitive-Behavioural Interventions for Smoking Cessation. Int. J. Environ. Res. Public Health 2009, 6, 1530-1538.

AMA Style

Ramon JM, Bruguera E. Real World Study to Evaluate the Effectiveness of Varenicline and Cognitive-Behavioural Interventions for Smoking Cessation. International Journal of Environmental Research and Public Health. 2009; 6(4):1530-1538.

Chicago/Turabian Style

Ramon, Josep Mª.; Bruguera, Eugeni. 2009. "Real World Study to Evaluate the Effectiveness of Varenicline and Cognitive-Behavioural Interventions for Smoking Cessation." Int. J. Environ. Res. Public Health 6, no. 4: 1530-1538.


Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert