Next Article in Journal
Toxicological Assessment of Toxic Element Residues in Swine Kidney and Its Role in Public Health Risk Assessment
Next Article in Special Issue
Epidemiological Methods: About Time
Previous Article in Journal / Special Issue
Very Low Dose Fetal Exposure to Chernobyl Contamination Resulted in Increases in Infant Leukemia in Europe and Raises Questions about Current Radiation Risk Models
Article Menu

Export Article

Open AccessArticle
Int. J. Environ. Res. Public Health 2009, 6(12), 3115-3126; doi:10.3390/ijerph6123115

Examining the Dynamic Association of BMI and Mortality in the Framingham Heart Study

1
Department of Biostatistics,University of Kansas Medical Center, Mail Stop 1026, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA
2
Department of Statistics, Florida State University,117 N. Woodward Ave. P.O. Box 3064330, Tallahassee, FL, 32306-4330, USA
3
Department of Preventive Medicine and Public Health, University of Kansas Medical Center, Mail Stop 1008, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA
*
Author to whom correspondence should be addressed.
Received: 6 November 2009 / Accepted: 3 December 2009 / Published: 7 December 2009
(This article belongs to the Special Issue Advances in Epidemiology)
View Full-Text   |   Download PDF [257 KB, uploaded 19 June 2014]   |  

Abstract

Based on the 40-year follow-up of the Framingham Heart Study (FHS), we used logistic regression models to demonstrate that different designs of an observational study may lead to different results about the association between BMI and all-cause mortality. We also used dynamic survival models to capture the time-varying relationships between BMI and mortality in FHS. The results consistently show that the association between BMI and mortality is dynamic, especially for men. Our analysis suggests that the dynamic property may explain part of the heterogeneity observed in the literature about the association of BMI and mortality.
Keywords: body mass index; mortality; time-varying association; dynamic survival models body mass index; mortality; time-varying association; dynamic survival models
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

He, J.; McGee, D.; Niu, X.; Choi, W. Examining the Dynamic Association of BMI and Mortality in the Framingham Heart Study. Int. J. Environ. Res. Public Health 2009, 6, 3115-3126.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top