Int. J. Environ. Res. Public Health 2009, 6(12), 3115-3126; doi:10.3390/ijerph6123115
Article

Examining the Dynamic Association of BMI and Mortality in the Framingham Heart Study

1 Department of Biostatistics,University of Kansas Medical Center, Mail Stop 1026, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA 2 Department of Statistics, Florida State University,117 N. Woodward Ave. P.O. Box 3064330, Tallahassee, FL, 32306-4330, USA 3 Department of Preventive Medicine and Public Health, University of Kansas Medical Center, Mail Stop 1008, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA
* Author to whom correspondence should be addressed.
Received: 6 November 2009; Accepted: 3 December 2009 / Published: 7 December 2009
(This article belongs to the Special Issue Advances in Epidemiology)
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Abstract: Based on the 40-year follow-up of the Framingham Heart Study (FHS), we used logistic regression models to demonstrate that different designs of an observational study may lead to different results about the association between BMI and all-cause mortality. We also used dynamic survival models to capture the time-varying relationships between BMI and mortality in FHS. The results consistently show that the association between BMI and mortality is dynamic, especially for men. Our analysis suggests that the dynamic property may explain part of the heterogeneity observed in the literature about the association of BMI and mortality.
Keywords: body mass index; mortality; time-varying association; dynamic survival models

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MDPI and ACS Style

He, J.; McGee, D.; Niu, X.; Choi, W. Examining the Dynamic Association of BMI and Mortality in the Framingham Heart Study. Int. J. Environ. Res. Public Health 2009, 6, 3115-3126.

AMA Style

He J, McGee D, Niu X, Choi W. Examining the Dynamic Association of BMI and Mortality in the Framingham Heart Study. International Journal of Environmental Research and Public Health. 2009; 6(12):3115-3126.

Chicago/Turabian Style

He, Jianghua; McGee, Daniel; Niu, Xufeng; Choi, Won. 2009. "Examining the Dynamic Association of BMI and Mortality in the Framingham Heart Study." Int. J. Environ. Res. Public Health 6, no. 12: 3115-3126.

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