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Epidemiological Methods: About Time
Department of Psychiatry and Behavioral Sciences, Stanford University, 1116 Forest Avenue, Palo Alto, CA 94301, USA
Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA 15213, USA
Received: 29 October 2009; Accepted: 24 December 2009 / Published: 31 December 2009
Abstract: Epidemiological studies often produce false positive results due to use of statistical approaches that either ignore or distort time. The three time-related issues of focus in this discussion are: (1) cross-sectional vs. cohort studies, (2) statistical significance vs. public health significance, and (3), how risk factors "work together" to impact public health significance. The issue of time should be central to all thinking in epidemiology research, affecting sampling, measurement, design, analysis and, perhaps most important, the interpretation of results that might influence clinical and public-health decision-making and subsequent clinical research.
Keywords: risk factors; statistical and clinical significance; effect sizes; moderators; mediators
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Kraemer, H.C. Epidemiological Methods: About Time. Int. J. Environ. Res. Public Health 2010, 7, 29-45.
Kraemer HC. Epidemiological Methods: About Time. International Journal of Environmental Research and Public Health. 2010; 7(1):29-45.
Kraemer, Helena Chmura. 2010. "Epidemiological Methods: About Time." Int. J. Environ. Res. Public Health 7, no. 1: 29-45.