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Int. J. Environ. Res. Public Health 2013, 10(11), 6044-6048; doi:10.3390/ijerph10116044
Communication

Lithium in Tap Water and Suicide Mortality in Japan

1,* , 1
, 2
, 3
 and 2
Received: 8 October 2013; in revised form: 5 November 2013 / Accepted: 7 November 2013 / Published: 12 November 2013
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Abstract: Lithium has been used as a mood-stabilizing drug in people with mood disorders. Previous studies have shown that natural levels of lithium in drinking water may protect against suicide. This study evaluated the association between lithium levels in tap water and the suicide standardized mortality ratio (SMR) in 40 municipalities of Aomori prefecture, which has the highest levels of suicide mortality rate in Japan. Lithium levels in the tap water supplies of each municipality were measured using inductively coupled plasma-mass spectrometry. After adjusting for confounders, a statistical trend toward significance was found for the relationship between lithium levels and the average SMR among females. These findings indicate that natural levels of lithium in drinking water might have a protective effect on the risk of suicide among females. Future research is warranted to confirm this association.
Keywords: lithium; suicide rate; Japan lithium; suicide rate; Japan
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Sugawara, N.; Yasui-Furukori, N.; Ishii, N.; Iwata, N.; Terao, T. Lithium in Tap Water and Suicide Mortality in Japan. Int. J. Environ. Res. Public Health 2013, 10, 6044-6048.

AMA Style

Sugawara N, Yasui-Furukori N, Ishii N, Iwata N, Terao T. Lithium in Tap Water and Suicide Mortality in Japan. International Journal of Environmental Research and Public Health. 2013; 10(11):6044-6048.

Chicago/Turabian Style

Sugawara, Norio; Yasui-Furukori, Norio; Ishii, Nobuyoshi; Iwata, Noboru; Terao, Takeshi. 2013. "Lithium in Tap Water and Suicide Mortality in Japan." Int. J. Environ. Res. Public Health 10, no. 11: 6044-6048.



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