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Mar. Drugs 2010, 8(5), 1526-1549; doi:10.3390/md8051526
Review

Halogenated Indole Alkaloids from Marine Invertebrates

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Received: 2 March 2010 / Revised: 19 April 2010 / Accepted: 23 April 2010 / Published: 28 April 2010
(This article belongs to the Special Issue Bioactive Halogenated Metabolites of Marine Origin)
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Abstract

This review discusses the isolation, structural elucidation, and biological activities of halogenated indole alkaloids obtained from marine invertebrates. Meridianins and related compounds (variolins, psammopemmins, and aplicyanins), as well as aplysinopsins and leptoclinidamines, are focused on. A compilation of the 13C-NMR spectral data of these selected natural indole alkaloids is also provided.
Keywords: marine invertebrates; halogenated indole alkaloids; structure elucidation; bioactivity; 13C-NMR spectral data marine invertebrates; halogenated indole alkaloids; structure elucidation; bioactivity; 13C-NMR spectral data
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Pauletti, P.M.; Cintra, L.S.; Braguine, C.G.; Filho, A.A.S.; Silva, M.L.A.; Cunha, W.R.; Januário, A.H. Halogenated Indole Alkaloids from Marine Invertebrates. Mar. Drugs 2010, 8, 1526-1549.

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