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Mar. Drugs 2017, 15(12), 392; doi:10.3390/md15120392

New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides

1
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
2
Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan
3
Department of Marine Biotechnology, National Kaohsiung Marine University, Kaohsiung 811, Taiwan
4
Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 4 November 2017 / Revised: 7 December 2017 / Accepted: 11 December 2017 / Published: 19 December 2017
(This article belongs to the Special Issue Natural Products from Coral Reef Organisms)
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Abstract

A novel cytotoxic diterpenoid, chabrolin A (1) (possessing an unprecedented terpenoid skeleton), as well as three new cytotoxic sesquiterpenoids, parathyrsoidins E–G (24), were isolated by cytotoxicity-guided fractionation from soft corals Nephthea chabroli and Paralemnalia thyrsoides. The structures of the new compounds were determined by extensive analysis of spectroscopic data. View Full-Text
Keywords: Nephthea chabroli; Paralemnalia thyrsoides; cytotoxicity Nephthea chabroli; Paralemnalia thyrsoides; cytotoxicity
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Lee, Y.-S.; Duh, T.-H.; Siao, S.-S.; Chang, R.-C.; Wang, S.-K.; Duh, C.-Y. New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides. Mar. Drugs 2017, 15, 392.

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