Next Article in Journal
Glycobiology of Reproductive Processes in Marine Animals: The State of the Art
Next Article in Special Issue
Antimalarial Activity of Axidjiferosides, New β-Galactosylceramides from the African Sponge Axinyssa djiferi
Previous Article in Journal
An Ethanol Extract Derived from Bonnemaisonia hamifera Scavenges Ultraviolet B (UVB) Radiation-Induced Reactive Oxygen Species and Attenuates UVB-Induced Cell Damage in Human Keratinocytes
Previous Article in Special Issue
Lipids of Prokaryotic Origin at the Base of Marine Food Webs
Mar. Drugs 2012, 10(12), 2846-2860; doi:10.3390/md10122846
Article

Palyosulfonoceramides A and B: Unique Sulfonylated Ceramides from the Brazilian Zoanthids Palythoa caribaeorum and Protopalyhtoa variabilis

1
,
1
,
2
,
1
,
1, 3
,
2,*  and 1
Received: 11 September 2012 / Revised: 19 November 2012 / Accepted: 3 December 2012 / Published: 14 December 2012
(This article belongs to the Special Issue Marine Lipids)
View Full-Text   |   Download PDF [927 KB, uploaded 24 February 2015]   |   Browse Figures

Abstract

The zoanthids Palythoa caribaeorum and Protopalythoa variabilis are among the most abundant marine species along the Brazilian coast. We now report the isolation and structure elucidation of two unprecedented sulfonylated ceramides, palyosulfonoceramide A (1) and palyosulfonoceramide B (2) from specimens collected off Brazil’s northeastern coast. The structures of 1 and 2 were established using a combination of NMR analyses, including: evaluation of 1H, 13C, 1H–1H COSY, 1H–13C HSQC, 1H–13C HMBC, and 1H–15N HMBC NMR spectra, high-resolution mass spectrometry and chemical degradation. In addition, we also isolated the corresponding known ceramides, N-((2S,3R,4E,8E)-1, 3-dihydroxyoctadeca-4,8-dien-2-yl)-hexadecanamide (3) and N-((2S,3R,4E)-1,3-dihydroxy octadeca-4-en-2-yl)-hexadecanamide (4), which provided further support for the assignments of 1 and 2.
Keywords: zoanthids; Palythoa caribaeorum; Protopalythoa variabilis; sulfonylated ceramides zoanthids; Palythoa caribaeorum; Protopalythoa variabilis; sulfonylated ceramides
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplement

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Almeida, J.G.L.; Maia, A.I.V.; Wilke, D.V.; Silveira, E.R.; Braz-Filho, R.; La Clair, J.J.; Costa-Lotufo, L.V.; Pessoa, O.D.L. Palyosulfonoceramides A and B: Unique Sulfonylated Ceramides from the Brazilian Zoanthids Palythoa caribaeorum and Protopalyhtoa variabilis. Mar. Drugs 2012, 10, 2846-2860.

View more citation formats

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert