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Sensors 2009, 9(4), 2437-2445; doi:10.3390/s90402437

Electrochemical Direct Determination of Catecholamines for the Early Detection of Neurodegenerative Diseases

Institute of Nanostructured Materials (ISMN) CNR Division 2, via del Castro Laurenziano 7, 00161 Rome, Italy
Received: 26 February 2009 / Revised: 1 April 2009 / Accepted: 7 April 2009 / Published: 7 April 2009
(This article belongs to the Special Issue State-of-the-Art Sensors Technology in Italy)
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Abstract

Smart (Nano) materials with biosensing functions posses enormous potential in development of new generation of stable biosensors, chemical sensors, and actuators. Recently, there is a considerable interest in using TiO2 nanostructured materials as a film-forming material since they have high surface area, optical transparency, high bio-compatibility, and relatively good conductivity. In this work, TiO2 nanostructured films were used as nanoporous electrodes to study the electron transfer mechanisms of dopamine. epinephrine and norepinephrine, in order to develop a new generation of chemical sensors. The interesting results obtained are described herein and the analytical characterization of these neurotransmitter sensors is reported. View Full-Text
Keywords: TiO2 nanostructured films; chemical sensors; monoamine-neurotransmitters; electrochemical transducers TiO2 nanostructured films; chemical sensors; monoamine-neurotransmitters; electrochemical transducers
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Curulli, A. Electrochemical Direct Determination of Catecholamines for the Early Detection of Neurodegenerative Diseases. Sensors 2009, 9, 2437-2445.

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