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Sensors 2010, 10(1), 526-543; doi:10.3390/s100100526
Review

Nano-Bio-Technology and Sensing Chips: New Systems for Detection in Personalized Therapies and Cell Biology

Received: 24 November 2009; in revised form: 30 December 2009 / Accepted: 5 January 2010 / Published: 12 January 2010
(This article belongs to the Special Issue Delft Workshop 2008-2009—Sensors and Imagers: a VLSI Perspective)
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Abstract: Further advances in molecular medicine and cell biology also require new electrochemical systems to detect disease biomarkers and therapeutic compounds. Microelectronic technology offers powerful circuits and systems to develop innovative and miniaturized biochips for sensing at the molecular level. However, microelectronic biochips proposed in the literature often do not show the right specificity, sensitivity, and reliability required by biomedical applications. Nanotechnology offers new materials and solutions to improve the surface properties of sensing probes. The aim of the present paper is to review the most recent progress in Nano-Bio-Technology in the area of the development of new electrochemical systems for molecular detection in personalized therapy and cell culture monitoring.
Keywords: biochip; DNA; enzymes; cytochromes; antibodies; carbon nanotubes; gold nano-particles; ethylene-glycol monolayers biochip; DNA; enzymes; cytochromes; antibodies; carbon nanotubes; gold nano-particles; ethylene-glycol monolayers
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Carrara, S. Nano-Bio-Technology and Sensing Chips: New Systems for Detection in Personalized Therapies and Cell Biology. Sensors 2010, 10, 526-543.

AMA Style

Carrara S. Nano-Bio-Technology and Sensing Chips: New Systems for Detection in Personalized Therapies and Cell Biology. Sensors. 2010; 10(1):526-543.

Chicago/Turabian Style

Carrara, Sandro. 2010. "Nano-Bio-Technology and Sensing Chips: New Systems for Detection in Personalized Therapies and Cell Biology." Sensors 10, no. 1: 526-543.



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