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Int. J. Mol. Sci. 2013, 14(8), 17085-17110; doi:10.3390/ijms140817085

Non-Coding RNAs and Cancer

Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 5 July 2013 / Revised: 1 August 2013 / Accepted: 8 August 2013 / Published: 19 August 2013
(This article belongs to the Special Issue Regulation by non-coding RNAs 2013)
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The discovery of the biological relevance of non-coding RNA (ncRNAs) molecules represents one of the most significant advances in contemporary molecular biology. Expression profiling of human tumors, based on the expression of miRNAs and other short or long ncRNAs, has identified signatures associated with diagnosis, staging, progression, prognosis, and response to treatment. In this review we will discuss the recent remarkable advancement in the understanding the biological functions of human ncRNAs in cancer, the mechanisms of expression and the therapeutic potential.
Keywords: small non-coding RNAs; long non-coding RNAs; cancer small non-coding RNAs; long non-coding RNAs; cancer
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Calore, F.; Lovat, F.; Garofalo, M. Non-Coding RNAs and Cancer. Int. J. Mol. Sci. 2013, 14, 17085-17110.

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