Int. J. Mol. Sci. 2013, 14(7), 15167-15178; doi:10.3390/ijms140715167
Article

Serum Oxidant and Antioxidant Status Following an All-Out 21-km Run in Adolescent Runners Undergoing Professional Training—A One-Year Prospective Trial

1 Dr. Stephen Hui Research Centre for Physical Recreation and Wellness, Department of Physical Education, Hong Kong Baptist University, Hong Kong, China 2 Faculty of Education, University of Macau, Macao, China 3 College of Physical Education, Liaoning Normal University, Dalian 116029, Liaoning, China 4 Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Parma 43126, Italy 5 College of Physical Education, Hebei Normal University, Shijiazhuang 050024, Hebei, China 6 School of Physical Education and Sports, Macao Polytechnic Institute, Macao, China
* Author to whom correspondence should be addressed.
Received: 6 June 2013; in revised form: 3 July 2013 / Accepted: 8 July 2013 / Published: 22 July 2013
(This article belongs to the Special Issue Oxidative Stress and Ageing)
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Abstract: This study investigated the 1-year longitudinal effect of professional training in adolescent runners on redox balance during intense endurance exercise. Changes in selected serum oxidant and antioxidant status in response to a 21-km running time trial in 10 runners (15.5 ± 1.3 years) undergoing professional training were evaluated twice in 12 months (pre- and post-evaluation). Venous blood samples were collected immediately before and 4-h following the 21-km run for analysis of serum concentrations of thiobarbituric acid-reactive substances (TBARS), xanthine oxidase (XO), catalase (CAT), reduced glutathione (GSH), superoxide dismutase (SOD), and total antioxidant capacity (T-AOC). In pre-evaluation trial, serum TBARS and SOD decreased after the 21-km run (p < 0.05) while XO, GSH, CAT and TAOC were unchanged. In post-evaluation trial, serum TBARS and SOD decreased, whereas XO and CAT increased post-exercise (p < 0.05). Furthermore, pre-exercise serum T-AOC, post-exercise serum XO, CAT, T-AOC (p < 0.05), and GSH (p = 0.057) appeared to be higher than the corresponding pre-evaluation values. The current findings suggest that a professional training regime in adolescent runners is not likely to jeopardize the development of their antioxidant defense. However, uncertainties in the maintenance of redox balance in runners facing increased exercise-induced oxidative stress as a consequence of training-induced enhancement of exercise capacity await further elucidation.
Keywords: adolescent; oxidative stress; antioxidant; endurance exercise

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MDPI and ACS Style

Tong, T.K.; Kong, Z.; Lin, H.; Lippi, G.; Zhang, H.; Nie, J. Serum Oxidant and Antioxidant Status Following an All-Out 21-km Run in Adolescent Runners Undergoing Professional Training—A One-Year Prospective Trial. Int. J. Mol. Sci. 2013, 14, 15167-15178.

AMA Style

Tong TK, Kong Z, Lin H, Lippi G, Zhang H, Nie J. Serum Oxidant and Antioxidant Status Following an All-Out 21-km Run in Adolescent Runners Undergoing Professional Training—A One-Year Prospective Trial. International Journal of Molecular Sciences. 2013; 14(7):15167-15178.

Chicago/Turabian Style

Tong, Tom K.; Kong, Zhaowei; Lin, Hua; Lippi, Giuseppe; Zhang, Haifeng; Nie, Jinlei. 2013. "Serum Oxidant and Antioxidant Status Following an All-Out 21-km Run in Adolescent Runners Undergoing Professional Training—A One-Year Prospective Trial." Int. J. Mol. Sci. 14, no. 7: 15167-15178.

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