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Int. J. Mol. Sci. 2009, 10(10), 4223-4256; doi:10.3390/ijms10104223
Review

Recent Advances in Synthetic Bioelastomers

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, 2,*  and 1,3,*
Received: 4 August 2009; in revised form: 30 August 2009 / Accepted: 8 September 2009 / Published: 29 September 2009
(This article belongs to the Special Issue Biodegradability of Materials)
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Abstract: This article reviews the degradability of chemically synthesized bioelastomers, mainly designed for soft tissue repair. These bioelastomers involve biodegradable polyurethanes, polyphosphazenes, linear and crosslinked poly(ether/ester)s, poly(ε-caprolactone) copolymers, poly(1,3-trimethylene carbonate) and their copolymers, poly(polyol sebacate)s, poly(diol-citrates) and poly(ester amide)s. The in vitro and in vivo degradation mechanisms and impact factors influencing degradation behaviors are discussed. In addition, the molecular designs, synthesis methods, structure properties, mechanical properties, biocompatibility and potential applications of these bioelastomers were also presented.
Keywords: bioelastomer; biodegradable; biocompatible; polyurethanes; polyphosphazenes; poly(ether ester); poly(ε-caprolactone); poly(1,3-trimethylene carbonate); poly(polyol sebacate)s; poly(diol-citrates); poly(ester amide)s bioelastomer; biodegradable; biocompatible; polyurethanes; polyphosphazenes; poly(ether ester); poly(ε-caprolactone); poly(1,3-trimethylene carbonate); poly(polyol sebacate)s; poly(diol-citrates); poly(ester amide)s
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Shi, R.; Chen, D.; Liu, Q.; Wu, Y.; Xu, X.; Zhang, L.; Tian, W. Recent Advances in Synthetic Bioelastomers. Int. J. Mol. Sci. 2009, 10, 4223-4256.

AMA Style

Shi R, Chen D, Liu Q, Wu Y, Xu X, Zhang L, Tian W. Recent Advances in Synthetic Bioelastomers. International Journal of Molecular Sciences. 2009; 10(10):4223-4256.

Chicago/Turabian Style

Shi, Rui; Chen, Dafu; Liu, Quanyong; Wu, Yan; Xu, Xiaochuan; Zhang, Liqun; Tian, Wei. 2009. "Recent Advances in Synthetic Bioelastomers." Int. J. Mol. Sci. 10, no. 10: 4223-4256.


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