Int. J. Mol. Sci. 2009, 10(10), 4223-4256; doi:10.3390/ijms10104223
Review

Recent Advances in Synthetic Bioelastomers

Rui Shi 1 email, Dafu Chen 1 email, Quanyong Liu 2 email, Yan Wu 2 email, Xiaochuan Xu 3 email, Liqun Zhang 2,* email and Wei Tian 1,3,* email
1 Laboratory of Bone Tissue Engineering of Beijing Research Institute of Traumatology and Orthopaedics, Beijing 100035, China 2 Beijing Key Laboratory on Preparation and Processing of Novel Polymer Materials at Beijing University of Chemical Technology, 100029, China 3 Department of Spine Surgery of Beijing JiShuiTan Hospital, the Fourth Clinical Medical College of Peking University, Beijing 100035, China
* Authors to whom correspondence should be addressed.
Received: 4 August 2009; in revised form: 30 August 2009 / Accepted: 8 September 2009 / Published: 29 September 2009
(This article belongs to the Special Issue Biodegradability of Materials)
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Abstract: This article reviews the degradability of chemically synthesized bioelastomers, mainly designed for soft tissue repair. These bioelastomers involve biodegradable polyurethanes, polyphosphazenes, linear and crosslinked poly(ether/ester)s, poly(ε-caprolactone) copolymers, poly(1,3-trimethylene carbonate) and their copolymers, poly(polyol sebacate)s, poly(diol-citrates) and poly(ester amide)s. The in vitro and in vivo degradation mechanisms and impact factors influencing degradation behaviors are discussed. In addition, the molecular designs, synthesis methods, structure properties, mechanical properties, biocompatibility and potential applications of these bioelastomers were also presented.
Keywords: bioelastomer; biodegradable; biocompatible; polyurethanes; polyphosphazenes; poly(ether ester); poly(ε-caprolactone); poly(1,3-trimethylene carbonate); poly(polyol sebacate)s; poly(diol-citrates); poly(ester amide)s

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Cite This Article

MDPI and ACS Style

Shi, R.; Chen, D.; Liu, Q.; Wu, Y.; Xu, X.; Zhang, L.; Tian, W. Recent Advances in Synthetic Bioelastomers. Int. J. Mol. Sci. 2009, 10, 4223-4256.

AMA Style

Shi R, Chen D, Liu Q, Wu Y, Xu X, Zhang L, Tian W. Recent Advances in Synthetic Bioelastomers. International Journal of Molecular Sciences. 2009; 10(10):4223-4256.

Chicago/Turabian Style

Shi, Rui; Chen, Dafu; Liu, Quanyong; Wu, Yan; Xu, Xiaochuan; Zhang, Liqun; Tian, Wei. 2009. "Recent Advances in Synthetic Bioelastomers." Int. J. Mol. Sci. 10, no. 10: 4223-4256.

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