Isolation and X-ray Crystal Structure of Tetrahydroisoquinoline Alkaloids from Calycotome Villosa Subsp. intermedias

doi:10.3390/90800650

This article is

freely available
re-usable

Molecules 2004, 9(8), 650-657; doi:10.3390/90800650

Article

Isolation and X-ray Crystal Structure of Tetrahydroisoquinoline Alkaloids from Calycotome Villosa Subsp. intermedias

Ali El Antri¹, Ibtissam Messouri¹, Mohamed Bouktaib¹, Rachid El Alami², Michael Bolte³, Brahim El Bali¹ and Mohammed Lachkar^1,*

¹ Laboratoire d´Analyses, d’Essais et d’Environnement (L.A.E.E.), Département de Chimie, Faculté des Sciences “Dhar Mehraz”, Université Sidi Mohamed Ben Abdellah, 30000 Fès, Morocco ² Département de Biologie, Faculté des Sciences “Dhar Mehraz”, Université Sidi Mohamed Ben Abdellah, 30000 Fès, Morocco ³ Institut für Organische Chemie, J. W. Goethe-Universität Frankfurt, Marie-Curie-Straße 11, 60439, Frankfurt/Main, Germany

* Author to whom correspondence should be addressed.

Received: 18 December 2003; in revised form: 6 July 2004 / Accepted: 11 July 2004 / Published: 31 July 2004

Download PDF Full-Text [192 KB, uploaded 20 June 2008 16:51 CEST]

Abstract: Two tetrahydroisoquinoline alkaloids were extracted from the alkaloid fraction of a methanol extract of the seeds of Calycotome Villosa Subsp. intermedia. Their structures were established as (R)-1-hydroxymethyl-7-8-dimethoxy-1,2,3,4-tetrahydro- isoquinoline (1) and (S)-7-hydroxymethyl-2-3-dimethoxy-7,8,9,10-tetrahydroisoquinoline chloride (2) by spectroscopic techniques and X-ray diffraction analysis.

Keywords: Calycotome villosa (Poiret) Link Subsp. Intermedia; alkaloids; tetrahydroisoquinoline; spectroscopy; X-ray crystal structure determination.

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

El Antri, A.; Messouri, I.; Bouktaib, M.; El Alami, R.; Bolte, M.; El Bali, B.; Lachkar, M. Isolation and X-ray Crystal Structure of Tetrahydroisoquinoline Alkaloids from Calycotome Villosa Subsp. intermedias. Molecules 2004, 9, 650-657.

AMA Style

El Antri A, Messouri I, Bouktaib M, El Alami R, Bolte M, El Bali B, Lachkar M. Isolation and X-ray Crystal Structure of Tetrahydroisoquinoline Alkaloids from Calycotome Villosa Subsp. intermedias. Molecules. 2004; 9(8):650-657.

Chicago/Turabian Style

El Antri, Ali; Messouri, Ibtissam; Bouktaib, Mohamed; El Alami, Rachid; Bolte, Michael; El Bali, Brahim; Lachkar, Mohammed. 2004. "Isolation and X-ray Crystal Structure of Tetrahydroisoquinoline Alkaloids from Calycotome Villosa Subsp. intermedias." Molecules 9, no. 8: 650-657.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert