Molecules 2002, 7(12), 871-884; doi:10.3390/71200871
Article

Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series

Davorka Pavlicic 1 , Jasna Dogan Koružnjak 1 , Zrinka Banic-Tomišic 1  and Grace Karminski-Zamola 2,* email
1 \"Pliva\" d.d., Research and Development, Prilaz baruna Filipovica 25, 10000 Zagreb, Croatia 2 Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 20, 10000 Zagreb, Croatia
* Author to whom correspondence should be addressed.
Received: 13 August 2002; in revised form: 28 November 2002 / Accepted: 4 December 2002 / Published: 31 December 2002
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Abstract: Three new heterocyclic substituted dianilides, namely 3-chloro-5-[1-(pfluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]thieno-[3,2-b]thiophene-2-carboxy-p-fluoroanilide (8), 1,2-bis{5-[2-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]-2-thienyl}ethene (13) and 6-chloro-2-{2-[3-chloro-2-(p-fluorophenyl-carbamoyl)-5-thieno[3,2-b]thienyl]-2-ethoxycarbonylethenyl}thieno[3,2-b]furan-5-carboxy-p-fluoroanilide (20) were prepared by multistep synthesis. The prepared dianilides are of particular interest for their potential to serve as the planar heteroaromatic core of DNA intercalators or groove binders.
Keywords: Amides; thieno[3; 2-b]thienyl- series; potential intercalators or groove binders

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MDPI and ACS Style

Pavlicic, D.; Koružnjak, J.D.; Banic-Tomišic, Z.; Karminski-Zamola, G. Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series. Molecules 2002, 7, 871-884.

AMA Style

Pavlicic D, Koružnjak JD, Banic-Tomišic Z, Karminski-Zamola G. Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series. Molecules. 2002; 7(12):871-884.

Chicago/Turabian Style

Pavlicic, Davorka; Koružnjak, Jasna D.; Banic-Tomišic, Zrinka; Karminski-Zamola, Grace. 2002. "Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series." Molecules 7, no. 12: 871-884.

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