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Molecules 2002, 7(12), 871-884; doi:10.3390/71200871
Article

Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series

1, 1, 1 and 2,*
Received: 13 August 2002; in revised form: 28 November 2002 / Accepted: 4 December 2002 / Published: 31 December 2002
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Abstract: Three new heterocyclic substituted dianilides, namely 3-chloro-5-[1-(pfluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]thieno-[3,2-b]thiophene-2-carboxy-p-fluoroanilide (8), 1,2-bis{5-[2-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]-2-thienyl}ethene (13) and 6-chloro-2-{2-[3-chloro-2-(p-fluorophenyl-carbamoyl)-5-thieno[3,2-b]thienyl]-2-ethoxycarbonylethenyl}thieno[3,2-b]furan-5-carboxy-p-fluoroanilide (20) were prepared by multistep synthesis. The prepared dianilides are of particular interest for their potential to serve as the planar heteroaromatic core of DNA intercalators or groove binders.
Keywords: Amides; thieno[3; 2-b]thienyl- series; potential intercalators or groove binders Amides; thieno[3; 2-b]thienyl- series; potential intercalators or groove binders
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Pavlicic, D.; Koružnjak, J.D.; Banic-Tomišic, Z.; Karminski-Zamola, G. Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series. Molecules 2002, 7, 871-884.

AMA Style

Pavlicic D, Koružnjak JD, Banic-Tomišic Z, Karminski-Zamola G. Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series. Molecules. 2002; 7(12):871-884.

Chicago/Turabian Style

Pavlicic, Davorka; Koružnjak, Jasna D.; Banic-Tomišic, Zrinka; Karminski-Zamola, Grace. 2002. "Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3,2-b]thiophene, Thieno[3,2-b]furan and 1,2-bis{5-[2-(2-Thienyl)ethenyl]2-thienyl}ethene Series." Molecules 7, no. 12: 871-884.


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