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Molecules 2000, 5(5), 727-729; doi:10.3390/50500727
Article

Synthesis of 2’-Modified Nucleotides

1,* , 1 and 1,2
Received: 4 May 2000; Accepted: 10 May 2000 / Published: 15 May 2000
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Abstract: We show in this work the development of modified building blocks for the synthesis of nuclease resistant hammerhead ribozymes. These modified monomers retain the 2’-OH which is essential for the activity of these molecules. Our final goal is to generate a catalytic antisense approach with potential application in gene therapy.
Keywords: Modified nucleotides; ribozymes Modified nucleotides; ribozymes
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Gallo, M.; Torres, H.; Iribarren, A. Synthesis of 2’-Modified Nucleotides. Molecules 2000, 5, 727-729.

AMA Style

Gallo M, Torres H, Iribarren A. Synthesis of 2’-Modified Nucleotides. Molecules. 2000; 5(5):727-729.

Chicago/Turabian Style

Gallo, Mariana; Torres, Héctor; Iribarren, Adolfo. 2000. "Synthesis of 2’-Modified Nucleotides." Molecules 5, no. 5: 727-729.


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