Synthesis of 2’-Modified Nucleotides
AbstractWe show in this work the development of modified building blocks for the synthesis of nuclease resistant hammerhead ribozymes. These modified monomers retain the 2’-OH which is essential for the activity of these molecules. Our final goal is to generate a catalytic antisense approach with potential application in gene therapy.
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Gallo, M.; Torres, H.; Iribarren, A. Synthesis of 2’-Modified Nucleotides. Molecules 2000, 5, 727-729.
Gallo M, Torres H, Iribarren A. Synthesis of 2’-Modified Nucleotides. Molecules. 2000; 5(5):727-729.Chicago/Turabian Style
Gallo, Mariana; Torres, Héctor; Iribarren, Adolfo. 2000. "Synthesis of 2’-Modified Nucleotides." Molecules 5, no. 5: 727-729.