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Molecules, Volume 5, Issue 12 (December 2000), Pages 1187-1532, Articles M172-M192

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Research

Jump to: Review, Other

Open AccessArticle Synthesis of 1-(2'-Deoxy-ß-D-ribofuranosyl)-1H-imidazo[4,5-d]-pyridazine-4,7(5H,6H)-dione: A Potential Building Block for Antisense Applications
Molecules 2000, 5(12), 1187-1193; doi:10.3390/51201187
Received: 28 August 2000 / Revised: 10 October 2000 / Accepted: 11 October 2000 / Published: 15 December 2000
Cited by 2 | PDF Full-text (59 KB)
Abstract
Synthesis of the title compound,1-(2'-deoxy-b-D-ribofuranosyl)-1H-imidazo[4,5-d]pyridazine-4,7(5H,6H)-dione (1), is reported. It was synthesized in five steps, commencing with methyl 1-(b-D-ribofuranosyl)imidazo-4,5-dicarboxylate (2). The 3',5'-hydroxyl groups of 2 were protected with a bis-silylating agent to form 3, which was then converted into the corresponding 2'-thionocarbonate derivative [...] Read more.
Synthesis of the title compound,1-(2'-deoxy-b-D-ribofuranosyl)-1H-imidazo[4,5-d]pyridazine-4,7(5H,6H)-dione (1), is reported. It was synthesized in five steps, commencing with methyl 1-(b-D-ribofuranosyl)imidazo-4,5-dicarboxylate (2). The 3',5'-hydroxyl groups of 2 were protected with a bis-silylating agent to form 3, which was then converted into the corresponding 2'-thionocarbonate derivative 5. The reduction of the latter with tri-n-butyltin hydride (to form 6), followed by silyl deprotection with tetra-nbutylammonium fluoride, afforded 7. Treatment of the latter with hydrazine hydrate yielded the target nucleoside 1. Full article
Open AccessArticle Synthesis Of Some Novel Silver-Cysteamine Complexes
Molecules 2000, 5(12), 1194-1200; doi:10.3390/51201194
Received: 22 March 2000 / Revised: 14 June 2000 / Accepted: 28 August 2000 / Published: 15 December 2000
Cited by 3 | PDF Full-text (93 KB)
Abstract
The aim of this research was to synthesize some new silver-cysteamine complexes of potential biological interest. Reactions were carried out between silver nitrate and cysteamine (2-aminoethanethiol hydrochloride) under different conditions of pH and mole ratios of the metal (silver) to the ligand [...] Read more.
The aim of this research was to synthesize some new silver-cysteamine complexes of potential biological interest. Reactions were carried out between silver nitrate and cysteamine (2-aminoethanethiol hydrochloride) under different conditions of pH and mole ratios of the metal (silver) to the ligand (cysteamine). Some novel silver-cysteamine complexes were made, and after characterization of the complexes by cyclic voltammetry, pH measurements, and microanalysis, it is now obvious that the mole ratio of the metal to the ligand in complexes is about four to three. Full article
Open AccessArticle Regioselectivity of Electrophilic Attack on 4-Methyl-1-Thioxo-1,2,4,5-Tetrahydro[1,2,4]Triazolo[4,3-A]Quinazolin-5-One Part 2: Reactions on Nitrogen Atom
Molecules 2000, 5(12), 1210-1223; doi:10.3390/51201210
Received: 26 July 2000 / Revised: 20 October 2000 / Accepted: 10 November 2000 / Published: 15 December 2000
Cited by 13 | PDF Full-text (260 KB)
Abstract
The regioselectivity on a cyclic thioamide group towards different electrophiles was studied on the model compound 4-methyl-1-thioxo-1,2,4,5-tetrahydro[1,2,4]triazolo [4,3-a]quinazolin-5-one 1. The examined compound 1 reacts with alkyl halides, amines in the presence of formaldehyde, acyl halides and compounds having activated double bonds to [...] Read more.
The regioselectivity on a cyclic thioamide group towards different electrophiles was studied on the model compound 4-methyl-1-thioxo-1,2,4,5-tetrahydro[1,2,4]triazolo [4,3-a]quinazolin-5-one 1. The examined compound 1 reacts with alkyl halides, amines in the presence of formaldehyde, acyl halides and compounds having activated double bonds to afford the N-substituted derivatives 2, 3 and 6. The regioselective reactions on nitrogen atom are due to strong Coulombic attraction. The reaction of 1 with amines in the presence of hydrogen peroxide afforded the aminolysis product 4. Compounds 1-6 were identified by FTIR, 1H NMR, 13C NMR, and mass spectroscopy. Full article
Open AccessArticle Chemistry of Substituted Quinolinones. Part VI. Synthesis and Nucleophilic Reactions of 4-Chloro-8-methylquinolin-2(1H)-one and its Thione Analogue
Molecules 2000, 5(12), 1224-1239; doi:10.3390/51201224
Received: 12 October 2000 / Revised: 2 November 2000 / Accepted: 9 November 2000 / Published: 18 December 2000
Cited by 3 | PDF Full-text (165 KB)
Abstract
The synthesis of 4-chloro-8-methylquinolin-2(1H)-one and its thione analogue is described. Some nucleophilic substitution reactions of the 4-chloro group were carried out to get new 4-substituted 2-quinolinones and quinolinethiones, such as 4-sulfanyl, hydrazino, azido and amino derivatives, which are of important [...] Read more.
The synthesis of 4-chloro-8-methylquinolin-2(1H)-one and its thione analogue is described. Some nucleophilic substitution reactions of the 4-chloro group were carried out to get new 4-substituted 2-quinolinones and quinolinethiones, such as 4-sulfanyl, hydrazino, azido and amino derivatives, which are of important synthetic use. The structure of the new compounds was established by their elemental analysis, IR and 1H-NMR spectra. Also the mass fragmentation pattern of some products is discussed. Full article
Open AccessArticle An Efficient Synthesis of 5-Alkoxycarbonyl-4-aryl-3,4-dihydropyrimidin-2(1H)-ones Catalyzed by KSF Montmorillonite
Molecules 2000, 5(12), 1240-1243; doi:10.3390/51201240
Received: 21 September 2000 / Revised: 27 October 2000 / Accepted: 8 November 2000 / Published: 18 December 2000
Cited by 21 | PDF Full-text (31 KB)
Abstract A mild and efficient catalytic method for synthesis of 5-alkoxycarbonyl-4-aryl-3,4- dihydropyrimidin-2(1H)-ones using KSF montmorillonite as catalyst is described. Full article
Open AccessArticle Improvement of a Critical Intermediate Step in the Synthesis of a Nitroxide-Based Spin-Labeled Deoxythymidine Analog
Molecules 2000, 5(12), 1244-1250; doi:10.3390/51201244
Received: 8 May 2000 / Revised: 13 November 2000 / Accepted: 14 November 2000 / Published: 18 December 2000
Cited by 7 | PDF Full-text (68 KB)
Abstract Methods to reduce the carboxylic acid moiety in 3-carboxy-2,2,5,5-tetramethylpyrrolin-1-oxyl to an alcohol as an intermediate toward the corresponding aldehyde have been explored and an improved method has been developed. Full article
Open AccessArticle Facile and Stereoselective Synthesis of Non-Racemic 3,3,3-Trifluoroalanine
Molecules 2000, 5(12), 1251-1258; doi:10.3390/51201251
Received: 6 October 2000 / Accepted: 7 November 2000 / Published: 18 December 2000
Cited by 5 | PDF Full-text (43 KB)
Abstract
A highly stereoselective enantiodivergent synthesis of non-racemic 3,3,3-trifluoroalanine 7 is reported. The methodology is based on the reduction, by 9-BBN or DIBAH, of the chiral sulfinimine 3 derived from ethyl trifluoropyruvate, followed by acidic hydrolysis of the resulting diastereomeric sulfinamides 4 and [...] Read more.
A highly stereoselective enantiodivergent synthesis of non-racemic 3,3,3-trifluoroalanine 7 is reported. The methodology is based on the reduction, by 9-BBN or DIBAH, of the chiral sulfinimine 3 derived from ethyl trifluoropyruvate, followed by acidic hydrolysis of the resulting diastereomeric sulfinamides 4 and 5. Full article
Open AccessArticle An Efficient Synthetic Strategy for the Preparation of Nucleic Acid-Encoded Peptide and Protein Libraries for In Vitro Evolution Protocols
Molecules 2000, 5(12), 1259-1264; doi:10.3390/51201259
Received: 6 November 2000 / Accepted: 6 November 2000 / Published: 18 December 2000
Cited by 3 | PDF Full-text (79 KB)
Abstract
We describe an improved synthetic strategy for the preparation of nucleic acid encoded peptide and protein libraries. A solid-phase format was used to prepare and purify a novel type of mRNA-template for in vitro mRNA-protein fusion synthesis. The present protocol simplifies and [...] Read more.
We describe an improved synthetic strategy for the preparation of nucleic acid encoded peptide and protein libraries. A solid-phase format was used to prepare and purify a novel type of mRNA-template for in vitro mRNA-protein fusion synthesis. The present protocol simplifies and accelerates the preparation of fusion libraries and should prove most useful for in vitro protein evolution procedures which involve repetitive cycles of fusion library preparation and selection. Full article
Open AccessArticle Relative Reactivities of Activated Carboxylic Acids in Amide-Forming Reactions Employed for the Synthesis of Tetraphenylporphyrin Libraries
Molecules 2000, 5(12), 1265-1280; doi:10.3390/51201265
Received: 3 November 2000 / Revised: 1 January 2000 / Accepted: 17 November 2000 / Published: 18 December 2000
Cited by 3 | PDF Full-text (224 KB)
Abstract
Presented here is a method for rapidly testing the reactivity of carboxylic acids in amide-forming reactions. For this, a mixture of two acids, one a reference compound, and one acid whose reactivity is unknown, are coupled to an aminoacylated tetrakis(paminophenyl) porphyrin under [...] Read more.
Presented here is a method for rapidly testing the reactivity of carboxylic acids in amide-forming reactions. For this, a mixture of two acids, one a reference compound, and one acid whose reactivity is unknown, are coupled to an aminoacylated tetrakis(paminophenyl) porphyrin under typical peptide coupling conditions. The product distribution in the resulting library is analyzed via MALDI-TOF mass spectrometry to reveal the relative reactivity. This rapid reactivity test requires sub-nanomole quantities of acids, does not involve cleavage from a support or any potentially biasing work-up, and is automatable. Thus, it is well suited for testing building blocks for combinatorial syntheses. Further, it is demonstrated that step-wise coupling can produce near-statistically distributed libraries of porphyrins when acids of very different reactivity are employed. Full article
Open AccessArticle Synthesis of Some Fused Pyrazoles and Isoxazoles
Molecules 2000, 5(12), 1281-1286; doi:10.3390/51201281
Received: 16 September 2000 / Revised: 30 October 2000 / Accepted: 8 November 2000 / Published: 18 December 2000
Cited by 32 | PDF Full-text (46 KB)
Abstract The α-keto methylene group in 3,5-diaryl-2-cyclohexenones 2 and 3,5-diarylcyclohexanones 8 have been used to obtain fused pyrazoles and isoxazoles. The new compounds were characterized by IR and 1H-NMR spectral data. Full article
Open AccessArticle Synthesis of α-Hydroxyacetosyringone
Molecules 2000, 5(12), 1287-1290; doi:10.3390/51201287
Received: 25 May 2000 / Accepted: 1 November 2000 / Published: 19 December 2000
Cited by 1 | PDF Full-text (25 KB)
Abstract A phytoalexin from papaya fruit has been synthesized in four steps; this procedure involved a Pummerer- type reaction. Full article
Open AccessArticle Synthesis and Photochemical Cyclization of a Novel Enyne-Carbodiimide
Molecules 2000, 5(12), 1372-1378; doi:10.3390/51201372
Received: 21 July 2000 / Accepted: 19 October 2000 / Published: 20 December 2000
Cited by 4 | PDF Full-text (111 KB)
Abstract The triplet sensitized cyclization of enyne-carbodiimide 4 leads to efficient formation of indoloquinoline 5 with concomittant loss of a methyl group. The efficient loss of the methyl group was explained using AM1 semiempirical calculations. Full article
Open AccessArticle The Relationship between Redox Potentials and Torsional Angles in 4,4’-Dimethyl N, N’-Alkylidene 2,2’-Bipyridinium Salts
Molecules 2000, 5(12), 1379-1385; doi:10.3390/51201379
Received: 27 January 2000 / Revised: 19 November 2000 / Accepted: 27 November 2000 / Published: 20 December 2000
Cited by 1 | PDF Full-text (155 KB)
Abstract
The redox potentials of 4,4’-dimethyl-N’N’-alkylidene bridged 2,2’-bipyridinium salts derivatives (DBPAs) can be controlled by changing the N, N’-alkylidene bridge length which changes the conformation of the DBPAs.. In this paper, the torsional angles between the two pyridine rings and the molecular energy [...] Read more.
The redox potentials of 4,4’-dimethyl-N’N’-alkylidene bridged 2,2’-bipyridinium salts derivatives (DBPAs) can be controlled by changing the N, N’-alkylidene bridge length which changes the conformation of the DBPAs.. In this paper, the torsional angles between the two pyridine rings and the molecular energy of DBPAs are calculated using a PC based software package (AccuModel 1.2). The relationship between torsional angle and N, N’-alkylidene bridge length is discussed. The molecular energy of DBPAs can also be related to the torsional angles (or N, N’-alkylidene bridge size). Some DBPAs had been synthesized and their redox potentials measured. The difference in potential between ethylene and propylene bridged DBPAs is large enough to make a organic diode through bilayer modified electrode. Full article
Open AccessArticle Study of Stereoselectivity in Organometallic Additions to 1,2-O-Isopropylidene-O-R-α-D-xylopentodialdo-1,4-furanose
Molecules 2000, 5(12), 1386-1398; doi:10.3390/51201386
Received: 2 August 2000 / Accepted: 8 December 2000 / Published: 21 December 2000
Cited by 12 | PDF Full-text (76 KB)
Abstract Diastereofacial selectivity of the addition of organometallic reagents to 1,2-Oisopropylidene-O-R-α-D-xylopentodialdo-1,4-furanoses (6) was studied. Full article
Open AccessArticle Substitution Effects on Reactivity of N-Acyl-2-amino-2-desoxyglucopyranoses. Quantum Chemical Study
Molecules 2000, 5(12), 1399-1407; doi:10.3390/51201399
Received: 22 November 2000 / Accepted: 28 November 2000 / Published: 21 December 2000
PDF Full-text (132 KB)
Abstract
Quantum mechanical calculations were carried out to study the molecular geometry and electronic structure of 2-amino-2-desoxyglucopyranose (AG) and the Nacetyl-, N-ethanoyl-, series of N-phthalimidoalkanoyl-AG. The total charge density, electrostatic potential, spatial distribution and positions of HOMO and LUMO of N-acyl-AGs with respect [...] Read more.
Quantum mechanical calculations were carried out to study the molecular geometry and electronic structure of 2-amino-2-desoxyglucopyranose (AG) and the Nacetyl-, N-ethanoyl-, series of N-phthalimidoalkanoyl-AG. The total charge density, electrostatic potential, spatial distribution and positions of HOMO and LUMO of N-acyl-AGs with respect to their substitutes yield information on the reactivity of the molecules. Full article
Open AccessArticle Halogeno Aldol Reaction of Ethyl Vinyl Ketone and Aldehydes Mediated by Titanium Tetrachloride
Molecules 2000, 5(12), 1408-1416; doi:10.3390/51201408
Received: 29 August 2000 / Revised: 6 December 2000 / Accepted: 6 December 2000 / Published: 22 December 2000
Cited by 4 | PDF Full-text (91 KB)
Abstract
A three-component halogeno aldol reaction has been developed by using titanium tetrachloride as the halogen source as well as the Lewis acid mediator. The dehydration and elimination of hydrogen chloride were inhibited by conducting the reaction at 0 °C in dichloromethane or [...] Read more.
A three-component halogeno aldol reaction has been developed by using titanium tetrachloride as the halogen source as well as the Lewis acid mediator. The dehydration and elimination of hydrogen chloride were inhibited by conducting the reaction at 0 °C in dichloromethane or at room temperature with a shortened reaction time. Seven examples were examined, giving good to high yields (61 - 92%) and modest stereoselectivity (syn/anti: 2.2/1.0 - 8.4/1.0). Full article
Open AccessArticle High-level Computational Study of the Site-, Facial- and Stereoselectivities for the Diels-Alder Reaction Between o-Benzoquinone and Norbornadiene
Molecules 2000, 5(12), 1417-1428; doi:10.3390/51201417
Received: 3 November 2000 / Accepted: 6 November 2000 / Published: 22 December 2000
Cited by 6 | PDF Full-text (407 KB)
Abstract
Ab initio and DFT quantum chemical calculations have been applied to a study of the Diels-Alder reaction of o-benzoquinone as diene and norbornadiene as dienophile. Transition states for the different reactions are located and activation energies estimated. The prefered exo-π-facial [...] Read more.
Ab initio and DFT quantum chemical calculations have been applied to a study of the Diels-Alder reaction of o-benzoquinone as diene and norbornadiene as dienophile. Transition states for the different reactions are located and activation energies estimated. The prefered exo-π-facial selectivity and exo,endo-stereoselectivity exhibited in this cycloaddition are readily predicted using RHF/3-21G or higher levels of calculations. Differences between experimentally observed results and calculations may be explained by the postulation of a second, nonconcerted biradical mechanism leading to formation of hetero Diels-Alder products. Full article
Open AccessArticle Synthesis and Antimicrobial Activity of Some New Benzimidazole Derivatives
Molecules 2000, 5(12), 1429-1438; doi:10.3390/51201429
Received: 10 January 2000 / Revised: 5 August 2000 / Accepted: 22 December 2000 / Published: 22 December 2000
Cited by 139 | PDF Full-text (117 KB)
Abstract
Reaction of 3-(2-methylbenzimidazol-1-yl)propanoic acid hydrazide (1) with CS2/KOH gave oxadiazole 2 which underwent Mannich reaction to give 3. Compound 2 was treated with hydrazine hydrate to give triazole 4 which was treated with both aldehydes and acetic anhydride to give [...] Read more.
Reaction of 3-(2-methylbenzimidazol-1-yl)propanoic acid hydrazide (1) with CS2/KOH gave oxadiazole 2 which underwent Mannich reaction to give 3. Compound 2 was treated with hydrazine hydrate to give triazole 4 which was treated with both aldehydes and acetic anhydride to give 5 and 6, respectively. Carbohydrazide 1 was reacted with ethyl acetoacetate, acetylacetone and aldehydes to give 7, 8 and 9, respectively. Cyclocondensation of 9 with thioglycolic and thiolactic acids gave 10 and 11, respectively. Some of these compounds showed potential antimicrobial activities. Full article

Review

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Open AccessReview Synthesis of Jasmonoides from Furan Derivatives
Molecules 2000, 5(12), 1201-1209; doi:10.3390/51201201
Received: 22 February 2000 / Revised: 21 July 2000 / Accepted: 22 August 2000 / Published: 15 December 2000
PDF Full-text (78 KB)
Abstract This paper presents applicability of commonly available furan derivatives, like 2-methyl furan, furaldehyde and 5-methylfuraldehyde in syntheses of jasmanoides. Full article
Open AccessReview Hydroxyquinones: Synthesis and Reactivity
Molecules 2000, 5(12), 1291-1330; doi:10.3390/51201291
Received: 30 June 2000 / Revised: 1 October 2000 / Accepted: 6 October 2000 / Published: 20 December 2000
Cited by 46 | PDF Full-text (343 KB)
Abstract
Quinones having hydroxy groups directly attached to the quinone ring constitute a very interesting class of quinoid compounds. A great number of hydroxyquinones are found in nature and the majority of them exhibit unique biological activity. Their syntheses and their main reactivity [...] Read more.
Quinones having hydroxy groups directly attached to the quinone ring constitute a very interesting class of quinoid compounds. A great number of hydroxyquinones are found in nature and the majority of them exhibit unique biological activity. Their syntheses and their main reactivity patterns are reviewed in this paper. Full article
Open AccessReview Organic Iodine(I, III, and V) Chemistry: 10 Years of Development at the Medical University of Warsaw, Poland
Molecules 2000, 5(12), 1331-1371; doi:10.3390/51201331
Received: 16 November 2000 / Accepted: 16 November 2000 / Published: 20 December 2000
Cited by 20 | PDF Full-text (286 KB)
Abstract
This review reports some novel (or considerably improved) methods for the synthesis of aromatic iodides, (dichloroiodo)arenes, (diacetoxyiodo)arenes, iodylarenes and diaryliodonium salts, as well as some facile, oxidative anion metatheses in crude diaryliodonium halides and, for comparison, potassium halides. All these new results [...] Read more.
This review reports some novel (or considerably improved) methods for the synthesis of aromatic iodides, (dichloroiodo)arenes, (diacetoxyiodo)arenes, iodylarenes and diaryliodonium salts, as well as some facile, oxidative anion metatheses in crude diaryliodonium halides and, for comparison, potassium halides. All these new results were obtained in our laboratory over the past decade (1990-2000). A full list of our papers dealing with the organic iodine(I, III and V) chemistry, covering exlusively the aromatic derivatives, is also provided. Full article
Open AccessReview Cyclohexenonic Long-Chain Fatty Alcohols as Neuronal Growth Stimulators
Molecules 2000, 5(12), 1439-1460; doi:10.3390/51201439
Received: 13 November 2000 / Revised: 7 December 2000 / Accepted: 7 December 2000 / Published: 22 December 2000
Cited by 24 | PDF Full-text (231 KB)
Abstract
Neurotrophic factors play an important role in the development and maintenance of neurons, thus providing a suitable therapeutic approach for the treatment of neurodegenerative diseases. However, their clinical use has revealed problematic because of a number of technical and biological disadvantages. Among [...] Read more.
Neurotrophic factors play an important role in the development and maintenance of neurons, thus providing a suitable therapeutic approach for the treatment of neurodegenerative diseases. However, their clinical use has revealed problematic because of a number of technical and biological disadvantages. Among the different strategies proposed to overcome such difficulties, the search for non-peptide substances with neurotrophic potential is giving promising results. Here we will expose major findings in this field, drawing special attention to cyclohexenonic long-chain fatty alcohols, a novel family of compounds that promote neuronal survival and neurite outgrowth. Full article

Other

Jump to: Research, Review

Open AccessShort Note 8,9-24,25-Diepoxy-Eupho-lanostan-3,4-olactone
Molecules 2000, 5(12), M172; doi:10.3390/M172
Received: 4 July 2000 / Accepted: 21 July 2000 / Published: 25 December 2000
PDF Full-text (90 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 5-[o-(1-L-Phenylalanylamino)ethoxyl]phenyl-10,15,20-triphenylporphyrin
Molecules 2000, 5(12), M173; doi:10.3390/M173
Received: 10 June 2000 / Accepted: 25 August 2000 / Published: 25 December 2000
PDF Full-text (95 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 3-Chloro-5-methoxy-1-benzo[b]thiophene-2-sulphonamide
Molecules 2000, 5(12), M174; doi:10.3390/M174
Received: 4 September 2000 / Accepted: 20 September 2000 / Published: 25 December 2000
PDF Full-text (88 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 2,4-Dinitrophenylhydrazine-benzo-9-crown-3
Molecules 2000, 5(12), M175; doi:10.3390/M175
Received: 12 June 2000 / Accepted: 28 September 2000 / Published: 25 December 2000
Cited by 1 | PDF Full-text (90 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note (u,l,l,u)-3,5-Diethyl-2,4,6-triphenyltetrahydropyran-2,4-diol
Molecules 2000, 5(12), M176; doi:10.3390/M176
Received: 18 July 2000 / Accepted: 21 July 2000 / Published: 25 December 2000
PDF Full-text (89 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 2-(4-Biphenyl-1-yl)-1,3-diazaspiro[4,5]dec-1-en-4-thione
Molecules 2000, 5(12), M177; doi:10.3390/M177
Received: 31 August 2000 / Accepted: 19 October 2000 / Published: 25 December 2000
PDF Full-text (89 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 2-Carbomethoxynor-31-lanosten-2-enol
Molecules 2000, 5(12), M178; doi:10.3390/M178
Received: 29 August 2000 / Accepted: 19 October 2000 / Published: 25 December 2000
PDF Full-text (80 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note bis[(N-Benzyloxycarbonyl)-(2R)-amino-4-methylpentyl]disulfide
Molecules 2000, 5(12), M179; doi:10.3390/M179
Received: 4 July 2000 / Accepted: 5 August 2000 / Published: 25 December 2000
PDF Full-text (90 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note bis[(N-Benzyloxycarbonyl)-(2S)-amino-4-methylpentyl]disulfide
Molecules 2000, 5(12), M180; doi:10.3390/M180
Received: 4 July 2000 / Accepted: 5 August 2000 / Published: 25 December 2000
PDF Full-text (90 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note A New Xanthone from Swertia decora
Molecules 2000, 5(12), M181; doi:10.3390/M181
Received: 29 August 2000 / Accepted: 19 October 2000 / Published: 25 December 2000
PDF Full-text (94 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note N-Benzotriazol-1-yl-methyl-1,2,3,4-tetrahydro-b-carboline
Molecules 2000, 5(12), M182; doi:10.3390/M182
Received: 29 September 2000 / Accepted: 16 November 2000 / Published: 25 December 2000
PDF Full-text (89 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 5-(Indol-3-yl)barbituric acid
Molecules 2000, 5(12), M183; doi:10.3390/M183
Received: 1 October 2000 / Accepted: 16 November 2000 / Published: 25 December 2000
Cited by 1 | PDF Full-text (87 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note E-(4-Methylbenzylidene)succinic anhydride
Molecules 2000, 5(12), M184; doi:10.3390/M184
Received: 26 September 2000 / Accepted: 16 November 2000 / Published: 25 December 2000
PDF Full-text (84 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 1,4-Bis(2',4',6'-trimethylphenylethynyl)benzene
Molecules 2000, 5(12), M185; doi:10.3390/M185
Received: 10 October 2000 / Accepted: 16 November 2000 / Published: 25 December 2000
PDF Full-text (88 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 2-Methyl-5-methylmercapto-3-dimethylsulfoxymethine-7-phenyl-1,2,4-triazepine
Molecules 2000, 5(12), M186; doi:10.3390/M186
Received: 20 September 2000 / Accepted: 16 November 2000 / Published: 25 December 2000
Cited by 2 | PDF Full-text (89 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 8a,9a-Epoxy Nor-31-lanosten-3-one
Molecules 2000, 5(12), M187; doi:10.3390/M187
Received: 29 October 2000 / Accepted: 30 November 2000 / Published: 25 December 2000
PDF Full-text (91 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 8a,9a-Epoxy Nor-31-lanosten-3,4-olactone
Molecules 2000, 5(12), M188; doi:10.3390/M188
Received: 29 October 2000 / Accepted: 30 November 2000 / Published: 25 December 2000
PDF Full-text (92 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 2-Carbomethoxy-8a,9a-epoxy Nor-31-lanosten-3-enol
Molecules 2000, 5(12), M189; doi:10.3390/M189
Received: 29 October 2000 / Accepted: 30 November 2000 / Published: 25 December 2000
PDF Full-text (92 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 8-Dihydro-3-methyl-7-amino-[1,2,4]triazino[3,4-b][1,3,4]thiadiazine
Molecules 2000, 5(12), M190; doi:10.3390/M190
Received: 23 October 2000 / Accepted: 30 November 2000 / Published: 25 December 2000
PDF Full-text (86 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note E,E-1-(4-Bromophenyl)-5-(3-indolyl)-1,4-pentadien-3-one
Molecules 2000, 5(12), M191; doi:10.3390/M191
Received: 20 September 2000 / Accepted: 30 November 2000 / Published: 25 December 2000
PDF Full-text (92 KB) | Supplementary Files
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessShort Note 24,31-Epoxy-24-methyl-elemo-lanost-8,9-ene-3-ol
Molecules 2000, 5(12), M192; doi:10.3390/M192
Received: 31 August 2000 / Accepted: 19 October 2000 / Published: 25 December 2000
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(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Open AccessMeeting Report Meeting Reports and Abstracts: Symposium on Applications of Porphyrins in Medicine and the Fourth School for Young Scientists on the Chemistry of Porphyrins and Related Compounds Ivanovo 2000
Molecules 2000, 5(12), 1461-1514; doi:10.3390/51201461
Published: 31 December 2000
Cited by 2 | PDF Full-text (375 KB)
Abstract
The Fourth School for Young Scientists on Chemistry of Porphyrins and Related Compounds Ivanovo 2000 and the Symposium "Application of Porphyrins in Medicine" were held at the facilities of Ivanovo State University of Chemistry and Technology and the Institute of the Solution [...] Read more.
The Fourth School for Young Scientists on Chemistry of Porphyrins and Related Compounds Ivanovo 2000 and the Symposium "Application of Porphyrins in Medicine" were held at the facilities of Ivanovo State University of Chemistry and Technology and the Institute of the Solution Chemistry of the Russian Academy of Sciences in Ples (Ivanovo region, Russia) from August 21 to August 27, 2000. About a hundred lecturers and young scientists from Russia, Belarus, Ukraine, Italy and Poland took part in the various sessions of the School and Symposium. The main centers (Moscow, Ivanovo, St-Petersburg, etc.) and directions of porphyrin investigation were well represented by Russian lecturers. The School program included lectures on synthesis, physico-chemical, coordination and application properties of porphyrins, phthalocyanines and related macroheterocyclic compounds. [...] Full article
Open AccessNew Book Received Thermodynamics and Kinetics for the Biological Sciences. By Gordon G. Hammes
Molecules 2000, 5(12), 1515-1516; doi:10.3390/51201515
Received: 22 December 2000 / Published: 31 December 2000
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Open AccessNew Book Received Physical Biochemistry: Principles and Applications. By David Sheehan
Molecules 2000, 5(12), 1517; doi:10.3390/51201517
Received: 22 December 2000 / Published: 31 December 2000
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Open AccessNew Book Received Combinatorial Chemistry. By Willi Bannwarth and Eduard Felder
Molecules 2000, 5(12), 1518-1519; doi:10.3390/51201518
Received: 22 December 2000 / Published: 31 December 2000
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Open AccessNew Book Received Carbohydrates in Chemistry and Biology. By Ernst, Beat / Hart, Gerald W. / Sinaÿ, Pierre
Molecules 2000, 5(12), 1520-1521; doi:10.3390/51201520
Received: 22 December 2000 / Published: 31 December 2000
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Open AccessNew Book Received Lewis Acids in Organic Synthesis. By Yamamoto, Hisashi
Molecules 2000, 5(12), 1522-1523; doi:10.3390/51201522
Received: 22 December 2000 / Published: 31 December 2000
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Open AccessNew Book Received Pharmaceuticals: Classes, Therapeutic Agents, Areas of Application. By McGuire, John L.
Molecules 2000, 5(12), 1524-1525; doi:10.3390/51201524
Received: 22 December 2000 / Published: 31 December 2000
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Open AccessNew Book Received Molecular Diversity in Drug Design. Edited by Philip M. Dean
Molecules 2000, 5(12), 1526-1527; doi:10.3390/51201526
Received: 22 December 2000 / Published: 31 December 2000
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Open AccessNew Book Received Advanced Organic Chemistry. Part A: Structure and Mechanisms. Fourth Edition. by Francis A. Carey
Molecules 2000, 5(12), 1528-1529; doi:10.3390/51201528
Received: 22 December 2000 / Published: 31 December 2000
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Open AccessNew Book Received Synthetic Organic Sonochemistry. Jean-Louis Luche
Molecules 2000, 5(12), 1530-1531; doi:10.3390/51201530
Received: 22 December 2000 / Published: 31 December 2000
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Open AccessNew Book Received Progress in Drug Research. By Jucker, E.
Molecules 2000, 5(12), 1532; doi:10.3390/51201532
Received: 22 December 2000 / Published: 31 December 2000
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