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Molecules 2018, 23(1), 80; doi:10.3390/molecules23010080

Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots

National Research Council (CNR), Institute of Biomolecular Chemistry (ICB), Via Campi Flegrei, 34, 80078 Pozzuoli (Naples), Italy
Laboratory of Chemistry and Environmental Chemistry (L.C.C.E), Department of Chemistry, Faculty of Sciences of the Matter, University of Batna 1, 05000 Batna, Algeria
Department of Pharmacy, University of Batna 2, Faculty of Medicine, 05000 Batna, Algeria
Author to whom correspondence should be addressed.
Received: 7 December 2017 / Revised: 27 December 2017 / Accepted: 28 December 2017 / Published: 30 December 2017
(This article belongs to the Special Issue Diversity of Terpenoids)
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The chemical study of Launaea acanthoclada from South-East Algeria led to the isolation of twelve oxygenated terpenoid compounds, including three new pentacyclic triterpenoids 13 with either lupane or ursane rearranged skeletons. The structure and the stereochemistry of these compounds were established by spectroscopic methods, including NMR techniques. The chemical pattern of L. acanthoclada is in accordance with the triterpenoid scenario of the genus Launaea embracing to date lupane, oleane, ursane and taraxastane skeletons. However, the carbon frameworks exhibited by new compounds 13 have never been reported from Launaea species. View Full-Text
Keywords: Launaea acanthoclada; triterpenoids; lupane; bauerane; structural elucidation; NMR Launaea acanthoclada; triterpenoids; lupane; bauerane; structural elucidation; NMR

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Zergainoh, N.; Ciavatta, M.L.; Carbone, M.; Bitam, F.; Aberkane, M.C.; Gavagnin, M. Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots. Molecules 2018, 23, 80.

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