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Molecules 2017, 22(5), 694; doi:10.3390/molecules22050694

Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth

1
Engineering Research Centre of Plant Growth Regulators, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China
2
Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China
*
Author to whom correspondence should be addressed.
Academic Editor: Roman Dembinski
Received: 7 April 2017 / Revised: 22 April 2017 / Accepted: 23 April 2017 / Published: 26 April 2017
(This article belongs to the Section Organic Synthesis)
View Full-Text   |   Download PDF [1049 KB, uploaded 26 April 2017]   |  

Abstract

A series of novel C-3-OH substituted gibberellin derivatives bearing an amide group were designed and synthesized from the natural product gibberellic acid (GA3). Their activities on the plant growth regulation of rice and Arabidopsis were evaluated in vivo. Among these compounds, 10d and 10f exhibited appreciable inhibitory activities on rice (48.6% at 100 μmol/L) and Arabidopsis (41.4% at 100 μmol/L), respectively. These results provide new insights into the design and synthesis of potential plant growth regulators. View Full-Text
Keywords: gibberellin derivatives; natural products; Huisgen reaction; amide; plant growth regulators gibberellin derivatives; natural products; Huisgen reaction; amide; plant growth regulators
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Tian, H.; Xu, Y.; Liu, S.; Jin, D.; Zhang, J.; Duan, L.; Tan, W. Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth. Molecules 2017, 22, 694.

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