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Molecules 2017, 22(10), 1691; doi:10.3390/molecules22101691

Facile and Green Synthesis of Saturated Cyclic Amines

1
Department of Biochemistry, Government College University, Faisalabad 38900, Pakistan
2
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad 38900, Pakistan
3
Department of Applied Chemistry, Government College University, Faisalabad 38900, Pakistan
4
Department of Home Economics, Government College Women University, Faisalabad 38900, Pakistan
*
Author to whom correspondence should be addressed.
Received: 19 September 2017 / Revised: 4 October 2017 / Accepted: 6 October 2017 / Published: 12 October 2017
(This article belongs to the Section Bioorganic Chemistry)

Abstract

Single-nitrogen containing saturated cyclic amines are an important part of both natural and synthetic bioactive compounds. A number of methodologies have been developed for the synthesis of aziridines, azetidines, pyrrolidines, piperidines, azepanes and azocanes. This review highlights some facile and green synthetic routes for the synthesis of unsubstituted, multisubstituted and highly functionalized saturated cyclic amines including one-pot, microwave assisted, metal-free, solvent-free and in aqueous media. View Full-Text
Keywords: cyclic amines; green synthesis; one-pot reactions; microwave assisted; solvent free cyclic amines; green synthesis; one-pot reactions; microwave assisted; solvent free
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Hameed, A.; Javed, S.; Noreen, R.; Huma, T.; Iqbal, S.; Umbreen, H.; Gulzar, T.; Farooq, T. Facile and Green Synthesis of Saturated Cyclic Amines. Molecules 2017, 22, 1691.

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