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Molecules 2015, 20(7), 12698-12731; doi:10.3390/molecules200712698

Tilting Plant Metabolism for Improved Metabolite Biosynthesis and Enhanced Human Benefit

Research Centre for Plant Growth and Development, University of KwaZulu-Natal Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa
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Author to whom correspondence should be addressed.
Academic Editor: Marcello Iriti
Received: 17 March 2015 / Revised: 29 April 2015 / Accepted: 12 May 2015 / Published: 13 July 2015
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Abstract

The immense chemical diversity of plant-derived secondary metabolites coupled with their vast array of biological functions has seen this group of compounds attract considerable research interest across a range of research disciplines. Medicinal and aromatic plants, in particular, have been exploited for this biogenic pool of phytochemicals for products such as pharmaceuticals, fragrances, dyes, and insecticides, among others. With consumers showing increasing interests in these products, innovative biotechnological techniques are being developed and employed to alter plant secondary metabolism in efforts to improve on the quality and quantity of specific metabolites of interest. This review provides an overview of the biosynthesis for phytochemical compounds with medicinal and other related properties and their associated biological activities. It also provides an insight into how their biosynthesis/biosynthetic pathways have been modified/altered to enhance production. View Full-Text
Keywords: bioactivity; biosynthesis; metabolism; plant secondary metabolite bioactivity; biosynthesis; metabolism; plant secondary metabolite
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Ncube, B.; Van Staden, J. Tilting Plant Metabolism for Improved Metabolite Biosynthesis and Enhanced Human Benefit. Molecules 2015, 20, 12698-12731.

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