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Molecules 2015, 20(7), 12436-12449; doi:10.3390/molecules200712436

In Vitro Studies of Chromone-Tetrazoles against Pathogenic Protozoa, Bacteria, and Fungi

1
Departamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, Col. Noria Alta, Guanajuato C.P. 36050, Gto., Mexico
2
Departamento de Biología, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, Col. Noria Alta, Guanajuato C.P. 36050, Gto., Mexico
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Christophe Dardonville
Received: 29 May 2015 / Revised: 25 June 2015 / Accepted: 26 June 2015 / Published: 8 July 2015
(This article belongs to the Special Issue Antiparasitic Agents)
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Abstract

In vitro studies to fourteen previously synthesized chromone-tetrazoles and four novel fluorine-containing analogs were conducted against pathogenic protozoan (Entamoeba histolytica), pathogenic bacteria (Pseudomonas aeruginosa, and Staphylococcus aureus), and human fungal pathogens (Sporothrix schenckii, Candida albicans, and Candida tropicalis), which have become in a serious health problem, mainly in tropical countries. View Full-Text
Keywords: chromone-tetrazoles; Ugi-azide reaction; antimicrobial activity; pathogenic protozoa; pathogenic bacteria; pathogenic fungi; tropical diseases chromone-tetrazoles; Ugi-azide reaction; antimicrobial activity; pathogenic protozoa; pathogenic bacteria; pathogenic fungi; tropical diseases
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Cano, P.A.; Islas-Jácome, A.; Rangel-Serrano, Á.; Anaya-Velázquez, F.; Padilla-Vaca, F.; Trujillo-Esquivel, E.; Ponce-Noyola, P.; Martínez-Richa, A.; Gámez-Montaño, R. In Vitro Studies of Chromone-Tetrazoles against Pathogenic Protozoa, Bacteria, and Fungi. Molecules 2015, 20, 12436-12449.

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