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Molecules 2015, 20(4), 5528-5553; doi:10.3390/molecules20045528

Tetrazolium Compounds: Synthesis and Applications in Medicine

1,†
,
1,†
and
1,2,*
1
Medicinal Chemistry and Pharmacology Institute, Inner Mongolia University for the Nationalities, Tongliao 028000, Inner Mongolia, China
2
Affiliated Hospital of Inner Mongolia University for Nationalities, Tongliao 028000, Inner Mongolia, China
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 9 December 2014 / Revised: 3 March 2015 / Accepted: 4 March 2015 / Published: 27 March 2015
(This article belongs to the Section Medicinal Chemistry)

Abstract

Tetrazoles represent a class of five-membered heterocyclic compounds with polynitrogen electron-rich planar structural features. This special structure makes tetrazole derivatives useful drugs, explosives, and other functional materials with a wide range of applications in many fields of medicine, agriculture, material science, etc. Based on our research works on azoles and other references in recent years, this review covers reported work on the synthesis and biological activities of tetrazole derivatives. View Full-Text
Keywords: tetrazole; sythesis; antibacterial; anti-inflammatory; anticancer; anticonvulsant tetrazole; sythesis; antibacterial; anti-inflammatory; anticancer; anticonvulsant
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Wei, C.-X.; Bian, M.; Gong, G.-H. Tetrazolium Compounds: Synthesis and Applications in Medicine. Molecules 2015, 20, 5528-5553.

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