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Open AccessCommunication
Molecules 2015, 20(3), 4450-4459; doi:10.3390/molecules20034450

New Sesquiterpenoids from Ambrosia artemisiifolia L.

1,2,†
,
1,†
,
3
and
1,2,*
1
Hunan Provincial Engineering & Technology Research Center for Biopesticide and Formulation Processing, Hunan Agricultural University, Changsha 410128, China
2
National Research Center of Engineering & Technology for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha 410128, China
3
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 19 January 2015 / Revised: 28 January 2015 / Accepted: 4 March 2015 / Published: 10 March 2015
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [737 KB, uploaded 10 March 2015]   |  

Abstract

A new pseudoguaianolide 1 and two new guaiane-type sesquiterpene glucosides 2 and 3, were isolated from the aerial parts of Ambrosia artemisiifolia L together with two known sesquiterpene dilactones 4 and 5. The new compounds were determined on the basis of spectroscopic and chemical methods to be 3β-acetoxy-4β-hydroxy-1α,7α, 10β,11αH-pseudoguaia-12,8β-olide (1), 1β,7β,9β,10β,13αH-guaia-4(5)-en-12,6β-olide 9-O-β-d-glucoside (2) and 4β-hydroxy-1α,5α,7α,9αH-guaia-10(14),11(13)-dien-12-acid 9-O-β-d-glucoside (3). The isolated compounds were evaluated for cytotoxicity against human promyelocytic leukemia HL-60 cell lines in vitro, but were all inactive. View Full-Text
Keywords: Ambrosia artemisiifolia L.; sesquiterpenoid; sesquiterpene glucoside Ambrosia artemisiifolia L.; sesquiterpenoid; sesquiterpene glucoside
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Ding, W.; Huang, R.; Zhou, Z.; Li, Y. New Sesquiterpenoids from Ambrosia artemisiifolia L.. Molecules 2015, 20, 4450-4459.

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