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Molecules 2015, 20(3), 3791-3810; doi:10.3390/molecules20033791

Lectins with Potential for Anti-Cancer Therapy

1
Department of Neurobiology, Physiology, and Behavior, University of California, Davis, CA 95616, USA
2
School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 2 December 2014 / Revised: 13 February 2015 / Accepted: 15 February 2015 / Published: 26 February 2015
(This article belongs to the Special Issue Lectins)
View Full-Text   |   Download PDF [929 KB, uploaded 27 February 2015]   |  

Abstract

This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins, Haliotis discus discus lectin, Polygonatum odoratum lectin, mistletoe lectin, and concanavalin A, fucose-binding Dicentrarchus labrax lectin, and Strongylocentrotus purpuratus lectin, Polygonatum odoratum lectin, and mistletoe lectin, Polygonatum odoratum lectin, autophagy inducing lectins include annexins and Polygonatum odoratum lectin. View Full-Text
Keywords: lectins; cancer cells; apoptosis; autophagy lectins; cancer cells; apoptosis; autophagy
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Yau, T.; Dan, X.; Ng, C.C.W.; Ng, T.B. Lectins with Potential for Anti-Cancer Therapy. Molecules 2015, 20, 3791-3810.

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