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Molecules 2015, 20(1), 358-365; doi:10.3390/molecules20010358

Flavonoids from Symplocos racemosa

1
College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, Korea
2
College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, Korea
3
College of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang, Gyeonggi-do 410-820, Korea
4
Department of Genetic Engineering, Sungkyunkwan University, Suwon 440-746, Korea
5
Department of Life Science, Hallym University, Chuncheon 200-702, Korea
6
Popa Mountain Park, Forest Department, Kyaukpadaung Township, Mandalay Division, Myanmar
7
Department of Forest Sciences, Seoul National University, Seoul 151-921, Korea
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 14 October 2014 / Accepted: 22 December 2014 / Published: 26 December 2014
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [884 KB, uploaded 26 December 2014]   |  

Abstract

A novel isoflavone glycoside, peseudobatigenin 7-O-[β-d-apiofuranosyl-(1''''→5''')-O-β-d-apiofuranosyl-(1'''→6'')]-β-d-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (216). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively. View Full-Text
Keywords: flavonoids; sympracemoside; Symplocos racemosa flavonoids; sympracemoside; Symplocos racemosa
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Jung, M.; Choi, J.; Chae, H.-S.; Cho, J.Y.; Kim, Y.-D.; Htwe, K.M.; Lee, W.-S.; Chin, Y.-W.; Kim, J.; Yoon, K.D. Flavonoids from Symplocos racemosa. Molecules 2015, 20, 358-365.

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