Marine Sponge Lectins: Actual Status on Properties and Biological Activities
AbstractMarine sponges are primitive metazoans that produce a wide variety of molecules that protect them against predators. In studies that search for bioactive molecules, these marine invertebrates stand out as promising sources of new biologically-active molecules, many of which are still unknown or little studied; thus being an unexplored biotechnological resource of high added value. Among these molecules, lectins are proteins that reversibly bind to carbohydrates without modifying them. In this review, various structural features and biological activities of lectins derived from marine sponges so far described in the scientific literature are discussed. From the results found in the literature, it could be concluded that lectins derived from marine sponges are structurally diverse proteins with great potential for application in the production of biopharmaceuticals, especially as antibacterial and antitumor agents. View Full-Text
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Gomes Filho, S.M.; Cardoso, J.D.; Anaya, K.; Silva do Nascimento, E.; de Lacerda, J.T.J.G.; Mioso, R.; Santi Gadelha, T.; de Almeida Gadelha, C.A. Marine Sponge Lectins: Actual Status on Properties and Biological Activities. Molecules 2015, 20, 348-357.
Gomes Filho SM, Cardoso JD, Anaya K, Silva do Nascimento E, de Lacerda JTJG, Mioso R, Santi Gadelha T, de Almeida Gadelha CA. Marine Sponge Lectins: Actual Status on Properties and Biological Activities. Molecules. 2015; 20(1):348-357.Chicago/Turabian Style
Gomes Filho, Sandro M.; Cardoso, Juscélio D.; Anaya, Katya; Silva do Nascimento, Edilza; de Lacerda, José T.J.G.; Mioso, Roberto; Santi Gadelha, Tatiane; de Almeida Gadelha, Carlos A. 2015. "Marine Sponge Lectins: Actual Status on Properties and Biological Activities." Molecules 20, no. 1: 348-357.