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Molecules 2014, 19(11), 17478-17535; doi:10.3390/molecules191117478

A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.

1
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China
2
School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 11 July 2014 / Revised: 13 August 2014 / Accepted: 15 August 2014 / Published: 30 October 2014
(This article belongs to the Section Metabolites)

Abstract

Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobial and blood fat reducing effects. To date, 316 GTs have been found and their similar chemical structures have proved difficult to elucidate. This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the literature published through January 2013 along with their structures, physiological activities and 13C-NMR spectral data. View Full-Text
Keywords: Ganoderma; triterpenes; chemical structure; 13C-NMR data; bioactivity Ganoderma; triterpenes; chemical structure; 13C-NMR data; bioactivity
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Xia, Q.; Zhang, H.; Sun, X.; Zhao, H.; Wu, L.; Zhu, D.; Yang, G.; Shao, Y.; Zhang, X.; Mao, X.; Zhang, L.; She, G. A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.. Molecules 2014, 19, 17478-17535.

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