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Molecules 2014, 19(1), 507-513; doi:10.3390/molecules19010507
Article

Characterization of a New Sesquiterpene and Antifungal Activities of Chemical Constituents from Dryopteris fragrans (L.) Schott

1,2,†
,
1,†
,
3
,
1
,
1
,
1
 and
1,*
1 Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Science, Heilongiang University, Harbin 150080, China 2 Center, Harbin Pharmaceutical Group, Harbin 150060, China 3 Pharmaceutical College, Harbin Medical University, Harbin 150086, China These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 14 October 2013 / Revised: 25 November 2013 / Accepted: 28 November 2013 / Published: 2 January 2014
(This article belongs to the Section Natural Products)
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Abstract

One new sesquiterpene and six known compounds were isolated from Dryopteris fragrans (L.) Schot. They were identified as 3-O-β-D-glucopyranosylalbicanol- 11-O-β-D-glucopyranoside (1), dihydroconiferylalcohol (2), (E)-3-(4-hydroxyphenyl)acrylic acid (3), esculetin (4), 5,7-dihydroxy-2-hydroxymethylchromone (5), eriodictyol (6) and isoorientin (7) by UV, MS, 1D-NMR and 2D-NMR spectroscopy. The antifungal activities of the seven isolated compounds were screened. Compounds 2, 3, 4 and 5 showed obvious activities against Microsporum canis and Epidermophyton floccosum.
Keywords: Dryopteris fragrans (L.) Schott; chemical constituents; activity screen; antifungal activity Dryopteris fragrans (L.) Schott; chemical constituents; activity screen; antifungal activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Huang, Y.-H.; Zeng, W.-M.; Li, G.-Y.; Liu, G.-Q.; Zhao, D.-D.; Wang, J.; Zhang, Y.-L. Characterization of a New Sesquiterpene and Antifungal Activities of Chemical Constituents from Dryopteris fragrans (L.) Schott. Molecules 2014, 19, 507-513.

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