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Molecules 2014, 19(1), 507-513; doi:10.3390/molecules19010507
Article

Characterization of a New Sesquiterpene and Antifungal Activities of Chemical Constituents from Dryopteris fragrans (L.) Schott

1,2,†
, 1,†
, 3
, 1
, 1
, 1
 and 1,*
1 Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Science, Heilongiang University, Harbin 150080, China 2 Center, Harbin Pharmaceutical Group, Harbin 150060, China 3 Pharmaceutical College, Harbin Medical University, Harbin 150086, China These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 14 October 2013 / Revised: 25 November 2013 / Accepted: 28 November 2013 / Published: 2 January 2014
(This article belongs to the Section Metabolites)
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Abstract

One new sesquiterpene and six known compounds were isolated from Dryopteris fragrans (L.) Schot. They were identified as 3-O-β-D-glucopyranosylalbicanol- 11-O-β-D-glucopyranoside (1), dihydroconiferylalcohol (2), (E)-3-(4-hydroxyphenyl)acrylic acid (3), esculetin (4), 5,7-dihydroxy-2-hydroxymethylchromone (5), eriodictyol (6) and isoorientin (7) by UV, MS, 1D-NMR and 2D-NMR spectroscopy. The antifungal activities of the seven isolated compounds were screened. Compounds 2, 3, 4 and 5 showed obvious activities against Microsporum canis and Epidermophyton floccosum.
Keywords: Dryopteris fragrans (L.) Schott; chemical constituents; activity screen; antifungal activity Dryopteris fragrans (L.) Schott; chemical constituents; activity screen; antifungal activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Huang, Y.-H.; Zeng, W.-M.; Li, G.-Y.; Liu, G.-Q.; Zhao, D.-D.; Wang, J.; Zhang, Y.-L. Characterization of a New Sesquiterpene and Antifungal Activities of Chemical Constituents from Dryopteris fragrans (L.) Schott. Molecules 2014, 19, 507-513.

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