Distinct Metabolites for Photoreactive l-Phenylalanine Derivatives in Klebsiella sp. CK6 Isolated from Rhizosphere of a Wild Dipterocarp Sapling
Abstract
:1. Introduction
2. Results and Discussion
2.1. Inoculation of l-phenylalanine as a Nitrogen Source for Klebsiella sp. CK6
2.2. Inoculation of Photoreactive l-phenylalanine Derivatives for Klebsiella sp. CK6
2.2.1. Inoculation of 4-Azido-l-phenylalanine as a Nitrogen Source for Klebsiella sp. CK6
2.2.2. Inoculation of 4-benzoyl-l-phenylalanine as a Nitrogen Source for Klebsiella sp. CK6
2.2.3. Inoculation of 4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]-l-phenylalanine as a Nitrogen Source for Klebsiella sp. CK6
2.2.4. Inoculation of 4-nitro-l-phenylalanine as a Nitrogen Source for Klebsiella sp. CK6
3. Experimental
3.1. General Procedures
3.2. Synthesis of 4-azido-l-phenylalanine(1a, Scheme 3)
3.3. Synthesis of 4-benzoyl-l-phenylalanine (2a, Scheme 3)
3.4. Synthesis of 4-[3-(trifluoromethyl)-3H-diazirin-3-yl]-l-phenylalanine (3a, Scheme 3)
3.5. Culture Medium and Growth Conditions
3.6. Extraction of Metabolites
3.7. 2-(4-Azidophenyl)acetic Acid (1b)
3.8. 2-(4-Benzoylphenyl)acetic acid (2b) and (4-(2-hydroxyethyl)phenyl)(phenyl)methanone (2c)
3.9. 2-Hydroxy-3-[4-[3-(trifluoromethyl)-3H-diazirin-3-yl]phenyl]propanoic Acid (3b)
3.10. 2-Hydroxy-3-(4-nitrophenyl)propanoic Acid (4d)
4. Conclusions
Acknowledgments
Conflicts of Interest
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Wang, L.; Hisano, W.; Murai, Y.; Sakurai, M.; Muto, Y.; Ikemoto, H.; Okamoto, M.; Murotani, T.; Isoda, R.; Kim, D.; et al. Distinct Metabolites for Photoreactive l-Phenylalanine Derivatives in Klebsiella sp. CK6 Isolated from Rhizosphere of a Wild Dipterocarp Sapling. Molecules 2013, 18, 8393-8401. https://doi.org/10.3390/molecules18078393
Wang L, Hisano W, Murai Y, Sakurai M, Muto Y, Ikemoto H, Okamoto M, Murotani T, Isoda R, Kim D, et al. Distinct Metabolites for Photoreactive l-Phenylalanine Derivatives in Klebsiella sp. CK6 Isolated from Rhizosphere of a Wild Dipterocarp Sapling. Molecules. 2013; 18(7):8393-8401. https://doi.org/10.3390/molecules18078393
Chicago/Turabian StyleWang, Lei, Wataru Hisano, Yuta Murai, Munenori Sakurai, Yasuyuki Muto, Haruka Ikemoto, Masashi Okamoto, Takashi Murotani, Reika Isoda, Dongyeop Kim, and et al. 2013. "Distinct Metabolites for Photoreactive l-Phenylalanine Derivatives in Klebsiella sp. CK6 Isolated from Rhizosphere of a Wild Dipterocarp Sapling" Molecules 18, no. 7: 8393-8401. https://doi.org/10.3390/molecules18078393