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Triterpenoids of Marine Origin as Anti-Cancer Agents
Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Korea
Department of Chemistry, Pukyong National University, Busan 608-737, Korea
* Author to whom correspondence should be addressed.
Received: 16 February 2013; in revised form: 10 June 2013 / Accepted: 27 June 2013 / Published: 4 July 2013
Abstract: Triterpenoids are the most abundant secondary metabolites present in marine organisms, such as marine sponges, sea cucumbers, marine algae and marine-derived fungi. A large number of triterpenoids are known to exhibit cytotoxicity against a variety of tumor cells, as well as anticancer efficacy in preclinical animal models. In this review efforts have been taken to review the structural features and the potential use of triterpenoids of marine origin to be used in the pharmaceutical industry as potential anti-cancer drug leads.
Keywords: triterpenoids; anti-cancer; cytotoxic; pharmacological agents; marine origin
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MDPI and ACS Style
Li, Y.-X.; Himaya, S.W.A.; Kim, S.-K. Triterpenoids of Marine Origin as Anti-Cancer Agents. Molecules 2013, 18, 7886-7909.
Li Y-X, Himaya SWA, Kim S-K. Triterpenoids of Marine Origin as Anti-Cancer Agents. Molecules. 2013; 18(7):7886-7909.
Li, Yong-Xin; Himaya, S. W.A.; Kim, Se-Kwon. 2013. "Triterpenoids of Marine Origin as Anti-Cancer Agents." Molecules 18, no. 7: 7886-7909.