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Molecules 2013, 18(7), 7886-7909; doi:10.3390/molecules18077886
Review

Triterpenoids of Marine Origin as Anti-Cancer Agents

1
, 2
 and 1,2,*
1 Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Korea 2 Department of Chemistry, Pukyong National University, Busan 608-737, Korea
* Author to whom correspondence should be addressed.
Received: 16 February 2013 / Revised: 10 June 2013 / Accepted: 27 June 2013 / Published: 4 July 2013
(This article belongs to the Special Issue Triterpenes and Triterpenoids)
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Abstract

Triterpenoids are the most abundant secondary metabolites present in marine organisms, such as marine sponges, sea cucumbers, marine algae and marine-derived fungi. A large number of triterpenoids are known to exhibit cytotoxicity against a variety of tumor cells, as well as anticancer efficacy in preclinical animal models. In this review efforts have been taken to review the structural features and the potential use of triterpenoids of marine origin to be used in the pharmaceutical industry as potential anti-cancer drug leads.
Keywords: triterpenoids; anti-cancer; cytotoxic; pharmacological agents; marine origin triterpenoids; anti-cancer; cytotoxic; pharmacological agents; marine origin
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Li, Y.-X.; Himaya, S.W.A.; Kim, S.-K. Triterpenoids of Marine Origin as Anti-Cancer Agents. Molecules 2013, 18, 7886-7909.

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