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Molecules 2013, 18(7), 7699-7710; doi:10.3390/molecules18077699
Article

Protection of Astaxanthin in Astaxanthin Nanodispersions Using Additional Antioxidants

1
, 2
 and 3,*
Received: 2 May 2013; in revised form: 21 June 2013 / Accepted: 1 July 2013 / Published: 2 July 2013
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Abstract: The protective effects of α-tocopherol and ascorbic acid on astaxanthin in astaxanthin nanodispersions produced via a solvent-diffusion technique and stabilized by a three-component stabilizer system, were studied either individually or in combination by using response surface methodology. Generally, both α-tocopherol and ascorbic acid could retard the astaxanthin degradation in astaxanthin nanodispersions. The results showed that the using α-tocopherol and ascorbic acid can be more efficient in increasing the chemical stability of nanodispersions in comparison to using them individually. Using a response surface methodology (RSM) response optimizer, it was seen that addition of ascorbic acid (ascorbic acid/astaxanthin w/w) and α-tocopherol (α-tocopherol/astaxanthin w/w) in proportions of 0.4 and 0.6, respectively, would give the maximum chemical stability to the studied astaxanthin nanodispersions.
Keywords: astaxanthin nanodispersions; chemical stability; ascorbic acid; α-tocopherol astaxanthin nanodispersions; chemical stability; ascorbic acid; α-tocopherol
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Anarjan, N.; Nehdi, I.A.; Tan, C.P. Protection of Astaxanthin in Astaxanthin Nanodispersions Using Additional Antioxidants. Molecules 2013, 18, 7699-7710.

AMA Style

Anarjan N, Nehdi IA, Tan CP. Protection of Astaxanthin in Astaxanthin Nanodispersions Using Additional Antioxidants. Molecules. 2013; 18(7):7699-7710.

Chicago/Turabian Style

Anarjan, Navideh; Nehdi, Imededdine A.; Tan, Chin P. 2013. "Protection of Astaxanthin in Astaxanthin Nanodispersions Using Additional Antioxidants." Molecules 18, no. 7: 7699-7710.



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