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Hepatoprotective Effects of Mushrooms
Department of Biochemistry, State University of Maringá, Maringá 87015-900, Brazil
Department of Biology, State University of Maringá, Maringá 87015-900, Brazil
Department of Nutrition, Federal University of the Southern Frontier, Realeza 85770-000, Brazil
* Author to whom correspondence should be addressed.
Received: 27 May 2013; in revised form: 26 June 2013 / Accepted: 27 June 2013 / Published: 1 July 2013
Abstract: The particular characteristics of growth and development of mushrooms in nature result in the accumulation of a variety of secondary metabolites such as phenolic compounds, terpenes and steroids and essential cell wall components such as polysaccharides, b-glucans and proteins, several of them with biological activities. The present article outlines and discusses the available information about the protective effects of mushroom extracts against liver damage induced by exogenous compounds. Among mushrooms, Ganoderma lucidum is indubitably the most widely studied species. In this review, however, emphasis was given to studies using other mushrooms, especially those presenting efforts of attributing hepatoprotective activities to specific chemical components usually present in the mushroom extracts.
Keywords: anthraquinol; anti-oxidant activity; ganoderenic acid; b-glucan; metabolism; natural products; oxidative stress
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Soares, A.A.; de Sá-Nakanishi, A.B.; Bracht, A.; da Costa, S.M.G.; Koehnlein, E.A.; de Souza, C.G.M.; Peralta, R.M. Hepatoprotective Effects of Mushrooms. Molecules 2013, 18, 7609-7630.
Soares AA, de Sá-Nakanishi AB, Bracht A, da Costa SMG, Koehnlein EA, de Souza CGM, Peralta RM. Hepatoprotective Effects of Mushrooms. Molecules. 2013; 18(7):7609-7630.
Soares, Andréia A.; de Sá-Nakanishi, Anacharis B.; Bracht, Adelar; da Costa, Sandra M.G.; Koehnlein, Eloá A.; de Souza, Cristina G.M.; Peralta, Rosane M. 2013. "Hepatoprotective Effects of Mushrooms." Molecules 18, no. 7: 7609-7630.