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A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Heilongtan, Kunming 650201, China
Xishuanbanna Tropical Botanical Garden, Chinese Academy of Sciences, Xuefu Road 88#, Kunming 650223, China
Key Laboratory of Ministry of Education on Traditional Chinese Medicine Resource and Compound Prescription, Pharmacy Faculty, Hubei University of Chinese Medicine, West Huangjiahu Road, Wuhan 430065, China
Department of Plant Sciences, Agricultural College, Guangxi University, East Daxue Road, Nanning 630004, China
These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 19 November 2012; in revised form: 7 December 2012 / Accepted: 26 December 2012 / Published: 18 January 2013
Abstract: A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)- O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2–11. Their structures were determined mainly by means of MS, 1D- and 2D-NMR data. Cytotoxicities of compounds 3 and 5–11 were tested on BGC-823, Hela and A549 cancer cell lines, the results showed that compound 8 was bioactive and its IC50 values were 6.9, 29.7 and 52.9 μM, respectively.
Keywords: Chamaecyparis obtusa var. breviramea f. crippsii; phenolic compounds; cytotoxicity
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Zhang, Y.-M.; Xu, J.; Xiao, L.; Zeng, G.-Z.; Sun, Z.-H.; Tan, N.-H. A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii. Molecules 2013, 18, 1255-1261.
Zhang Y-M, Xu J, Xiao L, Zeng G-Z, Sun Z-H, Tan N-H. A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii. Molecules. 2013; 18(1):1255-1261.
Zhang, Yu-Mei; Xu, Jian; Xiao, Lin; Zeng, Guang-Zhi; Sun, Zhang-Hua; Tan, Ning-Hua. 2013. "A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii." Molecules 18, no. 1: 1255-1261.