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A Review on Anti-Inflammatory Activity of Monoterpenes
Department of Physiology and Pathology, Federal University of Paraíba, CP 5009, CEP 58051-970, João Pessoa, Paraíba, Brazil
Department of Pharmacy, Federal University of Sergipe, CEP 49100-000, São Cristóvão, Sergipe, Brazil
* Author to whom correspondence should be addressed.
Received: 22 December 2012; in revised form: 4 January 2013 / Accepted: 5 January 2013 / Published: 18 January 2013
Abstract: Faced with the need to find new anti-inflammatory agents, great effort has been expended on the development of drugs for the treatment of inflammation. This disorder reduces the quality of life and overall average productivity, causing huge financial losses. In this review the anti-inflammatory activity of 32 bioactive monoterpenes found in essential oils is discussed. The data demonstrate the pharmacological potential of this group of natural chemicals to act as anti-inflammatory drugs.
Keywords: monoterpenes; essential oils; natural products; medicinal plants; anti-inflammatory activity; inflammation; cytokines; immunomodulatory activity; asthma; allergy
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de Cássia da Silveira e Sá, R.; Andrade, L.N.; de Sousa, D.P. A Review on Anti-Inflammatory Activity of Monoterpenes. Molecules 2013, 18, 1227-1254.
de Cássia da Silveira e Sá R, Andrade LN, de Sousa DP. A Review on Anti-Inflammatory Activity of Monoterpenes. Molecules. 2013; 18(1):1227-1254.
de Cássia da Silveira e Sá, Rita; Andrade, Luciana N.; de Sousa, Damião P. 2013. "A Review on Anti-Inflammatory Activity of Monoterpenes." Molecules 18, no. 1: 1227-1254.